What do systematic reviews say?

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

It is very uncertain whether finasteride 5 mg changes proportion of participants who reported an adverse event compared with flutamide 250 mg once to b.i.d. (very low certainty).

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  RR 3.87 [0.57, 26.24]
  3 studies · 115 participants
  Very low

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 136 participants
  Moderate

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 226 participants
  Very low

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 226 participants
  Moderate

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 110 participants
  High

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Moderate

Flutamide 250 mg b.i.d. vs placebo

Flutamide 250 mg b.i.d. may leads to higher participant‐reported improvement of hirsutism 4‐point Likert scale compared with placebo (low certainty).

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  RR 17 [1.11, 259.87]
  1 study · 20 participants
  Low

Flutamide 250 mg b.i.d. vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found