Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

319 questions · 323 findings · 28 reviews · Eyes and Vision

No studies found 85 · 26.3%GRADE not reported 10 · 3.1%Very low 80 · 24.8%Low 103 · 31.9%Moderate 41 · 12.7%High 4 · 1.2%

Therapeutic contact lens vs topical lubrication

Recurrence after complete or partial resolution · people with recurrent corneal erosion syndrome without previous surgical intervention

It is very uncertain whether therapeutic contact lens changes recurrence after complete or partial resolution compared with topical lubrication (very low certainty).

1 finding from 1 review

Phototherapeutic keratectomy vs alcohol delamination

Recurrence after complete or partial resolution · people with recurrent corneal erosion syndrome without previous surgical intervention

Phototherapeutic keratectomy showed no clear difference in recurrence after complete or partial resolution compared with alcohol delamination (low certainty).

1 finding from 1 review

Intervention not reported

3,4‐DAP (20 mg, single dose) versus placebo. Assessments made 30 minutes after taking the drug or placebo · people with acquired nystagmus
1 finding from 1 review

Intervention not reported

4‐AP (10 mg, single dose) versus 3,4‐DAP (10 mg, single dose) Assessments made at 45 and 90 minutes after taking the drug · people with acquired nystagmus
1 finding from 1 review