Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

304 questions · 309 findings · 37 reviews · Headline outcomes only

No studies found 80 · 25.9%GRADE not reported 8 · 2.6%Very low 88 · 28.5%Low 75 · 24.3%Moderate 54 · 17.5%High 4 · 1.3%

Intervention not reported

Total studies: 31* Total participants: 2816 No. interventions in network: 15 · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…

The intervention led to lower total studies: 31* Total participants: 2816 No. interventions in…; GRADE not reported.

1 finding from 1 review

Intervention not reported

Intervention Total studies: 9 Total participants: 883 · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

The intervention led to lower intervention Total studies: 9 Total participants: 883; GRADE not reported.

1 finding from 1 review

Intervention not reported

Total studies: 30 * Total participants: 2004 No. interventions in network: 14 · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…

The intervention led to lower total studies: 30 * Total participants: 2004 No. interventions in…; GRADE not reported.

1 finding from 1 review