Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

371 questions · 390 findings · 17 reviews · Orthodontics

No studies found 88 · 22.6%GRADE not reported 203 · 52.1%Very low 38 · 9.7%Low 38 · 9.7%Moderate 20 · 5.1%High 3 · 0.8%

Orthodontic treatment without extraction of permanent teeth vs Orthodontic treatment involving extraction of permanent teeth

Cephalometric measurements (ANB change and front teeth inclination changes) · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth)

The review found no eligible studies for this question.

1 finding from 1 review

Late treatment (one-phase) with removable functional appliance vs no treatment

Final ANB · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Late treatment (one-phase) with removable functional appliance may leads to lower final ANB compared with no treatment (low certainty).

1 finding from 1 review

Late treatment (one-phase) with fixed functional appliance vs no treatment

Final ANB · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Late treatment (one-phase) with fixed functional appliance showed no clear difference in final ANB compared with no treatment (low certainty).

1 finding from 1 review

Activator functional appliance vs Fixed functional appliance (FORSUS FRD EZ)

Final ANB · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Activator functional appliance led to lower final ANB compared with fixed functional appliance (FORSUS FRD EZ); GRADE not reported.

1 finding from 1 review

Removable functional appliance vs Fixed functional appliance

Final ANB · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Removable functional appliance may leads to lower final ANB compared with fixed functional appliance (low certainty).

1 finding from 1 review

Harvold Activator vs Frankel function regulator

Occlusion (net change in overjet, short term) · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Harvold Activator led to lower overjet change compared with frankel function regulator; GRADE not reported.

1 finding from 1 review

Late treatment (one-phase) with removable functional appliance vs no treatment

Incidence of incisal trauma · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

The review found no eligible studies for this question.

1 finding from 1 review

Removable functional appliance vs Fixed functional appliance

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Removable functional appliance may leads to higher final overjet compared with fixed functional appliance (low certainty).

1 finding from 1 review

Twin Block functional appliance vs Modified Twin Block appliances

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Twin Block functional appliance (conventional) showed no clear difference in final overjet compared with modified Twin Block appliances; GRADE not reported.

1 finding from 1 review

Late treatment (one-phase) with fixed functional appliance vs no treatment

Incidence of incisal trauma · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

The review found no eligible studies for this question.

1 finding from 1 review

Fixed functional appliance (FORSUS FRD) vs Intermaxillary elastics

Final ANB · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Fixed functional appliance (FORSUS FRD) showed no clear difference in final ANB compared with intermaxillary elastics; GRADE not reported.

1 finding from 1 review

Fixed functional appliance (FORSUS FRD) vs Intermaxillary elastics

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Fixed functional appliance (FORSUS FRD) showed no clear difference in final overjet compared with intermaxillary elastics; GRADE not reported.

1 finding from 1 review

Removable functional appliance vs Fixed functional appliance

Incidence of incisal trauma · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

The review found no eligible studies for this question.

1 finding from 1 review

Orthodontic treatment without extraction of permanent teeth vs No treatment (or delayed treatment)

Dento-occlusal results of treatment, measured with the PAR index · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth)

The review found no eligible studies for this question.

1 finding from 1 review

Activator functional appliance vs Fixed functional appliance (FORSUS FRD EZ)

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Activator functional appliance led to higher final overjet compared with fixed functional appliance (FORSUS FRD EZ); GRADE not reported.

1 finding from 1 review

Late treatment (one-phase) with removable functional appliance vs no treatment

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Late treatment (one-phase) with removable functional appliance may leads to lower final overjet compared with no treatment (low certainty).

1 finding from 1 review

Twin Block functional appliance vs Other functional appliances (Bionator, Herbst, R-appliance, Dynamax, Bite-Jumping)

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

Twin Block functional appliance showed no clear difference in final overjet compared with other functional appliances (Bionator, Herbst, R-appliance, Dynamax,… (low certainty).

1 finding from 1 review