Findings

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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4% SHMP chewing gum vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 4% SHMP chewing gum changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

1 finding from 1 review

10% HP strip vs 2% HP mouthwash/rinse

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

10% HP strip led to lower tooth whitening - assessed by the dentist compared with 2% HP mouthwash/rinse; GRADE not reported.

1 finding from 1 review

6% / 5.3% HP strip vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

6% / 5.3% HP strip may leads to higher tooth whitening - assessed by the dentist compared with placebo (low certainty).

1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs Placebo mouthwash

Number of participants with postoperative bleedings requiring intervention · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… probably leads to lower number of participants with postoperative bleedings requiring… compared with placebo (placebo solution/mouthwash) (moderate certainty).

1 finding from 1 review

6.5% HP strip vs 15% CP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 6.5% HP strip changes tooth whitening - assessed by the dentist compared with 15% CP gel in tray (very low certainty).

1 finding from 1 review

6% HP strip vs 18% CP paint-on gel

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 6% HP strip changes tooth whitening - assessed by the dentist compared with 18% CP paint-on gel (very low certainty).

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Calcium hydroxide + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with calcium hydroxide + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

Removable functional appliance vs Fixed functional appliance

Incidence of incisal trauma · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

The review found no eligible studies for this question.

1 finding from 1 review

Ball (stud) attachment system vs Telescopic attachment system

Prosthodontic maintenance: reline of implant overdenture (short term) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)

It is very uncertain whether ball (stud) attachment system changes prosthodontic maintenance: reline of implant overdenture (short term) compared with telescopic attachment system (very low certainty).

1 finding from 1 review

Orthodontic treatment without extraction of permanent teeth vs No treatment (or delayed treatment)

Dento-occlusal results of treatment, measured with the PAR index · Children (80% aged <= 16 years) with a Class II division 2 malocclusion (deep bite and retroclined upper front teeth)

The review found no eligible studies for this question.

1 finding from 1 review

GTR rm associated with bone substitutes + CAF vs SCTG + CAF

Keratinized tissue width change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

GTR rm associated with bone substitutes + CAF led to lower keratinized tissue width change compared with SCTG + CAF; GRADE not reported.

1 finding from 1 review