Findings

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Evidence found and GRADE certainty

4,752 questions · 6,648 findings · 688 reviews

No studies found 1,125 · 16.9%GRADE not reported 670 · 10.1%Very low 1,796 · 27%Low 1,685 · 25.3%Moderate 1,075 · 16.2%High 297 · 4.5%

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Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Number of women with total blood loss 1000 mL or more after randomisation · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Mean blood loss (mL) (trialist defined) · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Blood transfusion (red cell or whole blood) · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Side effects of the intervention (e.g. trauma, necrosis) ‐ fever · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

It is very uncertain whether intrauterine balloon tamponade (condom‐loaded catheter) changes side effects of the intervention (e.g. trauma, necrosis) ‐ fever compared with uterovaginal packing (intrauterine tamponade versus another… (very low certainty).

1 finding from 1 review

Doxycycline + SRP vs Amoxicillin + metronidazole + SRP

Adverse events · Adults with aggressive periodontitis

Doxycycline + SRP showed no clear difference in adverse events compared with amoxicillin + metronidazole + SRP; GRADE not reported.

1 finding from 1 review

Cyclosporin vs mycophenolate mofetil with pulse dexamethasone

Complete remission · idiopathic steroid‐resistant nephrotic syndrome in children

Cyclosporin showed no clear difference in treatment response at 52 weeks: complete remission (primary outcome… compared with mycophenolate mofetil with pulse dexamethasone (moderate certainty).

1 finding from 1 review

Cyclosporin vs mycophenolate mofetil with pulse dexamethasone

Partial remission ( · idiopathic steroid‐resistant nephrotic syndrome in children

Cyclosporin showed no clear difference in treatment response at 52 weeks: partial remission (primary outcome 3) compared with mycophenolate mofetil with pulse dexamethasone (moderate certainty).

1 finding from 1 review

Cyclosporin vs mycophenolate mofetil with pulse dexamethasone

Sustainable remission between 52 and 78 weeks: complete or partial remission (primary outcome 1, 2, 3) · idiopathic steroid‐resistant nephrotic syndrome in children

Cyclosporin showed no clear difference in sustainable remission between 52 and 78 weeks: complete or partial… compared with mycophenolate mofetil with pulse dexamethasone (moderate certainty).

1 finding from 1 review

Cyclosporin vs mycophenolate mofetil with pulse dexamethasone

CKD or death: 50% decline in GFR by 78 weeks · idiopathic steroid‐resistant nephrotic syndrome in children

Cyclosporin showed no clear difference in CKD or death: 50% decline in GFR by 78 weeks compared with mycophenolate mofetil with pulse dexamethasone (low certainty).

1 finding from 1 review

Cyclosporin vs mycophenolate mofetil with pulse dexamethasone

Adverse effects (weeks 0 to 26): serious infection requiring hospitalisation · idiopathic steroid‐resistant nephrotic syndrome in children

Cyclosporin showed no clear difference in adverse events (weeks 0 to 26): serious infection requiring… compared with mycophenolate mofetil with pulse dexamethasone (low certainty).

1 finding from 1 review