What do systematic reviews say?

Summary of findings: monoclonal antibody KB001‐A vs placebo

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 196 participants
  Very low

Summary of findings: nitric oxide vs placebo

Summary of findings: nitric oxide showed no clear difference in respiratory function mean change in FEV1 % predicted from baseline compared with placebo (low certainty).

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 12 participants
  Low

Summary of findings: nitric oxide vs placebo

It is very uncertain whether summary of findings: nitric oxide changes adverse events compared with placebo (very low certainty).

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 30 participants
  Very low

Summary of findings: nitric oxide vs placebo

The review found no eligible studies for this question.

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: nitric oxide vs placebo

The review found no eligible studies for this question.

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: nitric oxide vs placebo

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 30 participants
  Very low

Summary of findings: nitric oxide vs placebo

The review found no eligible studies for this question.

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: β‐carotene vs placebo

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 24 participants
  Low

Zinc vs placebo

It is very uncertain whether summary of findings: Zinc supplementation changes respiratory function mean FEV1 % predicted compared with placebo (very low certainty).

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 62 participants
  Very low

Zinc vs placebo

Summary of findings: Zinc supplementation showed no clear difference in adverse events number of participants hospitalised during the trial compared with placebo (moderate certainty).

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  RR 1.23 [0.51, 2.97]
  1 study · 37 participants
  Moderate

Zinc vs placebo

It is very uncertain whether summary of findings: Zinc supplementation changes need for antibiotics number of days on IV or oral antibiotics compared with placebo (very low certainty).

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  MD 0.52
  2 studies · 62 participants
  Very low

Zinc vs placebo

The review found no eligible studies for this question.

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Zinc vs placebo

The review found no eligible studies for this question.

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Zinc vs placebo

The review found no eligible studies for this question.

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: β‐carotene vs placebo

The review found no eligible studies for this question.

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: β‐carotene vs placebo

The review found no eligible studies for this question.

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings: β‐carotene vs placebo

The review found no eligible studies for this question.

• Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Interventions for promoting physical activity in people with chronic obstructive pulmonary disease (COPD) 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 411 participants
  Low

Intervention not reported

• Interventions for promoting physical activity in people with chronic obstructive pulmonary disease (COPD) 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 35 participants
  Low

Intervention not reported

• Interventions for promoting physical activity in people with chronic obstructive pulmonary disease (COPD) 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 131 participants
  Moderate