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Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

SULPIRIDE AUGMENTATION OF ANY ANTIPSYCHOTIC DRUG vs antipsychotics

No clinically important response to treatment ‐ short term · patients with schizophrenia

SULPIRIDE AUGMENTATION OF ANY ANTIPSYCHOTIC DRUG may leads to lower SENSITIVITY ‐ Global/mental state: No clinically important response… compared with ANY ANTIPSYCHOTIC DRUG (low certainty).

1 finding from 1 review

CLOZAPINE vs Typical antipsychotics

Relapse · patients with schizophrenia

CLOZAPINE probably leads to lower relapse ‐ short term compared with TYPICAL ANTIPSYCHOTICS ‐ OVERALL (moderate certainty).

4 findings from 1 review
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CLOZAPINE vs Typical antipsychotics

Global state: no improvement ‐ medium termAs defined in each study · patients with schizophrenia

CLOZAPINE probably leads to lower global impression: 1. Not clinically improved ‐ short term compared with TYPICAL ANTIPSYCHOTICS (moderate certainty).

3 findings from 1 review

CLOZAPINE vs Typical antipsychotics

Adverse effects 4. Salivation ‐ too much · patients with schizophrenia

CLOZAPINE probably leads to higher adverse effects 4. Salivation ‐ too much compared with TYPICAL ANTIPSYCHOTICS (moderate certainty).

2 findings from 1 review

CLOZAPINE vs Typical antipsychotics

Weight gain · patients with schizophrenia

CLOZAPINE probably leads to higher adverse effects 5. Weight gain compared with TYPICAL ANTIPSYCHOTICS (moderate certainty).

2 findings from 1 review

Summary of findings 3. AWARENESS OF INTERCESSORY PRAYER vs INTERCESSORY PRAYER

Clinical state: 1. Improved/not improved: intermediate or bad outcome · patients with scheduled to receive non‐emergency CABG

Summary of findings 4. AWARENESS OF INTERCESSORY PRAYER showed no clear difference in clinical state: 1. Improved/not improved: intermediate or bad outcome compared with INTERCESSORY PRAYER (moderate certainty).

1 finding from 1 review

Summary of findings 3. AWARENESS OF INTERCESSORY PRAYER vs INTERCESSORY PRAYER

Clinical state: 2. Significant complications (readmission to CCU) · patients with scheduled to receive non‐emergency CABG

Summary of findings 4. AWARENESS OF INTERCESSORY PRAYER showed no clear difference in clinical state: 2. Significant complications (readmission to CCU) compared with INTERCESSORY PRAYER (moderate certainty).

1 finding from 1 review

Summary of findings 1. INTERCESSORY PRAYER (CONTEMPORANEOUS ) vs usual care

Clinical state: 1. Improved/not improved: intermediate or bad outcome · patients with various illnesses

Summary of findings 1. INTERCESSORY PRAYER (CONTEMPORANEOUS ) showed no clear difference in clinical state: 1. Improved/not improved: intermediate or bad outcome compared with STANDARD CARE (low certainty).

1 finding from 1 review

Summary of findings 1. INTERCESSORY PRAYER (CONTEMPORANEOUS ) vs usual care

Clinical state: 2. Significant complications (readmission to CCU) · patients with various illnesses

Summary of findings 1. INTERCESSORY PRAYER (CONTEMPORANEOUS ) showed no clear difference in clinical state: 2. Significant complications (readmission to CCU) compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

Summary of findings 3. AWARENESS OF INTERCESSORY PRAYER vs usual care

Clinical state: 1. Improved/not improved: intermediate or bad outcome · patients with scheduled to receive non‐emergency CABG

Summary of findings 3. AWARENESS OF INTERCESSORY PRAYER showed no clear difference in clinical state: 1. Improved/not improved: intermediate or bad outcome compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

Summary of findings 3. AWARENESS OF INTERCESSORY PRAYER vs usual care

Clinical state: 2. Significant complications (readmission to CCU) · patients with scheduled to receive non‐emergency CABG

Summary of findings 3. AWARENESS OF INTERCESSORY PRAYER showed no clear difference in clinical state: 2. Significant complications (readmission to CCU) compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

Day hospitals vs OUT‐PATIENT CARE

Hospital admissions · patients with people with schizophrenia near or on discharge

DAY HOSPITAL showed no clear difference in service use: 1a. Admitted to hospital during study ‐ by 6 months compared with OUT‐PATIENT CARE (moderate certainty).

3 findings from 1 review