Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,760 questions · 8,065 findings · 1,036 reviews

No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Superelastic NiTi arch wire vs Titanium-niobium-tantalum-zirconium (TiNbTaZr) arch wire

Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review

Coated superelastic NiTi wire (BioCosmetic, Titanol, TP Aesthetic or Tooth Tone) vs A different coated superelastic NiTi wire

Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review

Multistrand stainless steel wire vs Wires of other materials (conventional stainless steel, superelastic NiTi, thermoelastic NiTi)

Alignment rate · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
1 finding from 1 review
  • Initial arch wires used in orthodontic treatment with fixed appliances 2024 · Cochrane All outcomes
    6 weeks to 6 months
    Multistrand StSt versus other materials (conventional StSt, superelastic NiTi, thermoelastic NiTi); alignment rate not pooled due to clinical heterogeneity (Cobb 1998; Evans 1998; Quintao 2005; West 1995); results…
    4 studies · 281 participants
    Very low

High-dose vitamin D3 supplementation during pregnancy (2400 IU/day from pregnancy week 24 to 1 week postpartum, in addition to the recommended 400 IU/day) vs Low-dose (standard) vitamin D supplementation as recommended in national pregnancy guidelines

Dental caries · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

The review found no eligible studies for this question.

2 findings from 1 review

Balloon (Foley or ATAD) vs low‐dose vaginal misoprostol

Serious neonatal morbidity or perinatal death · third trimester induction of labour in women with a viable fetus

It is very uncertain whether balloon (Foley or ATAD) changes serious neonatal morbidity or perinatal death compared with low‐dose vaginal misoprostol (very low certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Vaginal delivery not achieved within 24 hours · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) probably leads to higher vaginal delivery not achieved within 24 hours compared with low‐dose oral misoprostol (moderate certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Uterine hyperstimulation with fetal heart rate changes · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) showed no clear difference in uterine hyperstimulation with FHR changes compared with low‐dose oral misoprostol (low certainty).

1 finding from 1 review