Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings ‐ Hydroxyurea and phlebotomy vs transfusion and chelation

Pain alteration: proportion experiencing serious VOC or sickle‐related pain events · adults and children with sickle cell disease and an increased risk of stroke

Summary of findings ‐ Hydroxyurea and phlebotomy may leads to higher pain alteration: proportion experiencing serious VOC or… compared with transfusion and chelation (low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Has used any health service in previous 1 to 12 months · children (0 to 17 years) and adults (≥ 18 years) or households

Summary of findings: unconditional cash transfer showed no clear difference in has used any health service in previous 1 to 12 months compared with no unconditional cash transfer: primary outcomes (low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Engages in child labour · children (0 to 17 years) and adults (≥ 18 years) or households

It is very uncertain whether summary of findings: unconditional cash transfer changes engages in child labour compared with no unconditional cash transfer: secondary outcomes (very low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Adult works · children (0 to 17 years) and adults (≥ 18 years) or households

It is very uncertain whether summary of findings: unconditional cash transfer changes adult works compared with no unconditional cash transfer: secondary outcomes (very low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Is extremely poor · children (0 to 17 years) and adults (≥ 18 years) or households

Summary of findings: unconditional cash transfer may leads to lower is extremely poor compared with no unconditional cash transfer: secondary outcomes (low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Is moderately stunted · children (0 to 17 years) and adults (≥ 18 years) or households

It is very uncertain whether summary of findings: unconditional cash transfer changes is moderately stunted compared with no unconditional cash transfer: primary outcomes (very low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Has had any illness in previous 2 weeks to 3 months · children (0 to 17 years) and adults (≥ 18 years) or households

Summary of findings: unconditional cash transfer probably leads to lower has had any illness in previous 2 weeks to 3 months compared with no unconditional cash transfer: primary outcomes (moderate certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Has been food secure in previous month · children (0 to 17 years) and adults (≥ 18 years) or households

Summary of findings: unconditional cash transfer may leads to higher has been food secure in previous month compared with no unconditional cash transfer: primary outcomes (low certainty).

1 finding from 1 review

Summary of findings: unconditional cash transfer vs no unconditional cash transfer: primary outcomes

Attends school · children (0 to 17 years) and adults (≥ 18 years) or households

Summary of findings: unconditional cash transfer probably leads to higher attends school compared with no unconditional cash transfer: secondary outcomes (moderate certainty).

1 finding from 1 review

Recombinant human growth hormone vs placebo or no intervention

Measures of mineral metabolism: change in serum phosphate mmol/L · children with X‐linked hypophosphataemia

It is very uncertain whether summary of findings ‐ recombinant growth hormone changes measures of mineral metabolism: change in serum phosphate mmol/L compared with placebo or no intervention (very low certainty).

1 finding from 1 review