Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Lietofix cream vs iodoform dressing

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

Lietofix cream may leads to higher proportion of wounds healed at 30 days compared with iodoform dressing (low certainty).

3 findings from 1 review

Negative pressure wound therapy vs conventional open wound healing

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether topical negative pressure wound therapy changes proportion of wounds healed at 30 days compared with conventional open wound healing (very low certainty).

3 findings from 1 review

Hydrogel dressings vs povidone‐iodine

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether hydrogel dressing changes time to wound healing (days) compared with wound cleaning with 10% povidone iodine (very low certainty).

1 finding from 1 review

Hydrogel dressings vs povidone‐iodine

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

3 findings from 1 review

Hydrogel dressings vs povidone‐iodine

Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether hydrogel dressing changes adverse effects (surgical site infection or allergic reaction) compared with wound cleaning with 10% povidone iodine (very low certainty).

1 finding from 1 review

Platelet‐rich plasma gel vs absorbent sterile cotton gauze

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

Platelet‐rich plasma gel may leads to higher time to wound healing (days) compared with absorbent sterile cotton gauze (low certainty).

1 finding from 1 review

Platelet‐rich plasma gel vs absorbent sterile cotton gauze

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

3 findings from 1 review

Platelet‐rich plasma gel vs absorbent sterile cotton gauze

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

1 finding from 1 review

Gentamicin‐impregnated collagen sponge vs no dressing

Time to complete healing · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

It is very uncertain whether gentamicin‐impregnated collagen sponge changes time to wound healing (days) compared with no dressing (very low certainty).

1 finding from 1 review

Gentamicin‐impregnated collagen sponge vs no dressing

Proportion of wounds healed · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease

The review found no eligible studies for this question.

3 findings from 1 review