Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,556 questions · 2,794 findings · 119 reviews · All outcomes

No studies found 489 · 17.5%GRADE not reported 1,719 · 61.5%Very low 399 · 14.3%Low 128 · 4.6%Moderate 58 · 2.1%High 1 · 0%

1-stage (non-submerged) implant placement vs 2-stage (submerged) implant placement

Prosthesis failure · People with dental implants

1-stage (non-submerged) implant placement showed no clear difference in prosthesis failure compared with 2-stage (submerged) implant placement (moderate certainty).

1 finding from 1 review

Vertical distraction osteogenesis vs Autogenous onlay bone graft (mandibular ramus)

Marginal bone level change · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical distraction osteogenesis showed no clear difference in 1-year post-loading bone level changes compared with autogenous onlay bone graft (mandibular ramus); GRADE not reported.

2 findings from 1 review

Prophylactic aciclovir (oral or intravenous) vs placebo

Viral isolates (HSV isolates identified, with or without clinical symptoms) · Patients being treated for cancer (predominantly haematological malignancies)

Prophylactic aciclovir (oral or intravenous) led to lower viral isolates (HSV isolates identified, with or without clinical… compared with placebo; GRADE not reported.

1 finding from 1 review

Effervescent tablets vs No treatment (immersion in distilled water)

Microbial counts (total aerobes, anaerobes, yeasts) · Complete denture (CD) wearers in a nursing home
1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    Moore 1984: soaking methods resulted in significant reduction of total aerobes and anaerobes versus distilled water (paired t test, P < 0.05); three soaking methods (Clorox and Calgon, Polident, Effedent) were less…
    1 study · 12 participants
    GRADE not reported

Aciclovir (oral or intravenous) for treatment vs placebo

Amount of analgesia · Patients being treated for cancer with established oral HSV infection (bone marrow transplant recipients / immunocompromised)

The review found no eligible studies for this question.

1 finding from 1 review

Brushing vs Effervescent tablets

Visual plaque score · American complete denture (CD) wearers
1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    12 weeks
    Tarbet 1984 compared brushing with two types of effervescent tablets. No standard deviations were reported and therefore no data were entered for this outcome. Brushing was associated with significantly lower plaque…
    1 study · 75 participants
    GRADE not reported

Inlay autogenous bone graft (iliac crest) vs Inlay bone substitute (Bio-Oss block)

Major complications · Patients with atrophic posterior mandibles (5 to 7 mm above the mandibular canal) needing implants

Inlay autogenous bone graft (iliac crest) showed no clear difference in major complications compared with inlay bone substitute (Bio-Oss block); GRADE not reported.

1 finding from 1 review

Enzyme cleanser vs Placebo / sham solution

Microbial counts (hyphae and bacteria) · Institutionalised elderly wearing maxillary complete dentures (CD)
1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    12 weeks
    Lower hyphal and bacterial scores were also found for 'E' when compared with 'Plac' after 12 weeks. It was not possible to extract adequate data as the investigators did not provide standard deviations.
    1 study
    GRADE not reported

Prophylactic valaciclovir (lower dose) vs Prophylactic valaciclovir (higher dose)

Viral isolates · Patients being treated for cancer (acute leukaemia; chemotherapy or stem-cell transplantation)
1 finding from 1 review

Prophylactic aciclovir (oral or intravenous) vs Prophylactic valaciclovir (oral)

Presence/absence of HSV oral lesions · Patients being treated for cancer (predominantly haematological malignancies)

Prophylactic aciclovir (oral or intravenous) showed no clear difference in presence/absence of HSV oral lesions compared with prophylactic valaciclovir (oral); GRADE not reported.

1 finding from 1 review

Enzyme cleanser vs Brushing

Denture plaque · Wearers of maxillary and mandibular complete dentures (CD)
1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    Standard deviations were not reported for the relevant data so these were not included in the analysis. Reduction of plaque scores was associated with enzyme concentration (ANOVA, P < 0.001). Brushing alone and…
    1 study
    GRADE not reported

Autogenous bone block from the chin + resorbable barrier vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Prosthesis/implant failure (1 year) · Patients with horizontally resorbed maxillary sites needing single implants

Autogenous bone block from the chin + resorbable barrier showed no clear difference in prosthesis/implant failure (1 year) compared with 100% Bio-Oss + resorbable barrier; GRADE not reported.

1 finding from 1 review

Any denture cleansing method (mechanical or chemical) vs Another therapy, placebo, or no treatment

Adverse effects · Adults (over 18) wearing complete dentures (CD) or removable partial dentures (RPD)

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for cleaning dentures in adults 2009 · Cochrane All outcomes
    Noticeable absence of reports about adverse effects; no included study assessed the extent of adverse effects (for example the aftertaste of sodium hypochlorite, or mechanical or chemical damage to denture materials)…
    0 studies
    No studies found

Silicone surfactant cleanser vs Placebo / sham solution

Visual plaque score · Complete denture (CD) wearers

Silicone surfactant cleanser led to lower visual plaque score compared with placebo / sham solution; GRADE not reported.

2 findings from 1 review

Vertical GBR with non-resorbable titanium-reinforced barriers vs Vertical GBR with resorbable barriers supported by osteosynthesis plates

Complication at augmented site · Patients with vertically deficient posterior/anterior mandibular ridges needing implants

Vertical GBR with non-resorbable titanium-reinforced barriers showed no clear difference in complication at augmented site compared with vertical GBR with resorbable barriers supported by osteosynthesis…; GRADE not reported.

1 finding from 1 review

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer implants (vertical augmentation) vs Short implants (8 to 11 mm) without augmentation

No improvement of facial appearance (3 weeks) · Patients with atrophic (resorbed) mandibles needing implants

Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to lower no improvement of facial appearance (3 weeks) compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.

1 finding from 1 review

Horizontal bone augmentation (any technique) vs No augmentation

Outcome not reported · Patients with horizontally resorbed maxillary sites needing single implants

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic aciclovir (oral or intravenous) vs placebo

Presence/absence of HSV oral lesions · Patients being treated for cancer (predominantly haematological malignancies)

Prophylactic aciclovir (oral or intravenous) led to lower presence/absence of HSV oral lesions compared with placebo; GRADE not reported.

1 finding from 1 review