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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

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No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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2% lidocaine, 1:80,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Success of local anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 2% lidocaine, 1:80,000 epinephrine changes success of local anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

Midfacial soft tissue changes (facial profile landmarks: pronasale, subnasale, stomion superius, labrale superius) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…

Maxillary distraction osteogenesis showed no clear difference in midfacial soft tissue changes (facial profile landmarks: pronasale,… compared with orthognathic surgery (conventional Le Fort I osteotomy); GRADE not reported.

1 finding from 1 review

Biodentine vs Diode laser

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, premature tooth loss (Niranjani 2015); no clinical/radiological failure outcome; RR 2.00 (0.20 to 20.33)
    1 study · 40 participants
    GRADE not reported

Metapex (calcium hydroxide/iodoform) vs RC Fill (ZOE with iodoform)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Calcium hydroxide (CH)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes clinical failure compared with calcium hydroxide (CH) (very low certainty).

1 finding from 1 review

Calcium-enriched mixture (CEM) cement vs Mineral trioxide aggregate (MTA)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth
2 findings from 1 review

GTR rm associated with bone substitutes + CAF vs GTR rm + CAF

Attachment change · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm)

GTR rm associated with bone substitutes + CAF showed no clear difference in clinical attachment level change compared with GTR rm + CAF; GRADE not reported.

1 finding from 1 review

Biodentine vs Tempophore

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in clinical failure compared with tempophore; GRADE not reported.

1 finding from 1 review

Total-etching 36% phosphoric acid + acetone-based total-etch adhesive vs Non-rinse conditioner + acetone-based total-etch adhesive

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether total-etching 36% phosphoric acid + acetone-based total-etch adhesive changes clinical failure compared with non-rinse conditioner + acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

4% prilocaine plain vs 2% lidocaine, 1:100,000 epinephrine

Success of local anaesthesia, absence of pain (clinical testing of healthy pulps, hard and soft tissues) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

4% prilocaine plain may leads to lower success of local anaesthesia, absence of pain (clinical testing of… compared with 2% lidocaine, 1:100,000 epinephrine (low certainty).

1 finding from 1 review

10% CP gel in tray vs 7.5% HP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 10% CP gel in tray changes tooth whitening - assessed by the dentist compared with 7.5% HP gel in tray (very low certainty).

1 finding from 1 review

Tooth-supported removable partial denture: different impression material, same final-impression technique vs The same technique with an alternative final-impression material

Outcome not reported · Partially edentulous people requiring a removable partial denture

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical debridement plus local antimicrobial (minocycline microspheres or doxycycline gel) vs Mechanical debridement alone

Clinical attachment level (CAL) · Adults treated for periodontitis and receiving supportive periodontal therapy (SPT)

Mechanical debridement plus local antimicrobial (minocycline… showed no clear difference in clinical attachment level (mm) compared with mechanical debridement alone (low certainty).

1 finding from 1 review

Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Zinc oxide and eugenol (ZOE) pulpectomy

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Ferric sulphate/MTA pulpotomy showed no clear difference in radiological failure compared with zinc oxide and eugenol (ZOE) pulpectomy; GRADE not reported.

1 finding from 1 review