Findings

What do systematic reviews say?

510 questions · 513 findings · 62 reviews · Headline outcomes only

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No studies found 96 · 18.7%GRADE not reported 13 · 2.5%Very low 181 · 35.3%Low 121 · 23.6%Moderate 69 · 13.5%High 33 · 6.4%

Summary of findings: liposomal bupivacaine vs placebo

Total postoperative opioid consumption over first 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 189 participants
Very low

Summary of findings: liposomal bupivacaine vs placebo

Incidence of adverse events within 30 days of surgery · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 382 participants
Low

Summary of findings: liposomal bupivacaine vs bupivacaine

Cumulative pain score from the end of operation (0 hours) to 72 hours (NRS 0 to 10) · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 379 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Serious adverse events · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 583 participants
Moderate

Needle aspiration vs incision and drainage

Recurrence · patients older than 8 years with peritonsillar abscess

It is very uncertain whether needle aspiration changes primary outcome: recurrence rate compared with incision and drainage (very low certainty).

1 finding from 1 review

Needle aspiration versus incision and drainage for the treatment of peritonsillar abscess 2016 · Cochrane Headline outcomes only
RR 3.74
10 studies · 612 participants
Very low

Needle aspiration vs incision and drainage

Adverse events associated with treatment · patients older than 8 years with peritonsillar abscess

1 finding from 1 review

Needle aspiration versus incision and drainage for the treatment of peritonsillar abscess 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 226 participants
Very low

Needle aspiration vs incision and drainage

Secondary outcome: time to resumption of normal diet · patients older than 8 years with peritonsillar abscess

1 finding from 1 review

Needle aspiration versus incision and drainage for the treatment of peritonsillar abscess 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 124 participants
Very low

Needle aspiration vs incision and drainage

Secondary outcome: complications of the disease process · patients older than 8 years with peritonsillar abscess

1 finding from 1 review

Needle aspiration versus incision and drainage for the treatment of peritonsillar abscess 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 170 participants
Very low

Needle aspiration vs incision and drainage

Secondary outcome: symptom scores (Multiple different outcome scales used) · patients older than 8 years with peritonsillar abscess

1 finding from 1 review

Needle aspiration versus incision and drainage for the treatment of peritonsillar abscess 2016 · Cochrane Headline outcomes only
no estimate extracted
1 participants
Very low

Statins vs placebo

Change in BCVA (lower logMAR indicate better vision) · People aged 50 years or older with age‐related macular degeneration

1 finding from 1 review

Statins for age‐related macular degeneration 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low

Statins vs placebo

Onset and progression of AMD · People aged 50 years or older with age‐related macular degeneration

1 finding from 1 review

Statins for age‐related macular degeneration 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 114 participants
Low

Statins vs placebo

Adverse outcomes · People aged 50 years or older with age‐related macular degeneration

1 finding from 1 review

Statins for age‐related macular degeneration 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 114 participants
Low

Intervention not reported

Adverse drug events · older people (aged 65 years or older) living in care homes

1 finding from 1 review

Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1228 participants
Low

Intervention not reported

Hospital admissions · older people (aged 65 years or older) living in care homes

1 finding from 1 review

Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 7606 participants
Low

Intervention not reported

Mortality · older people (aged 65 years or older) living in care homes

1 finding from 1 review

Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 6805 participants
Low

Intervention not reported

Quality of life · older people (aged 65 years or older) living in care homes

1 finding from 1 review

Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 586 participants
Low

Intervention not reported

Medication‐related problems · older people (aged 65 years or older) living in care homes

1 finding from 1 review

Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 6640 participants
Low

Intervention not reported

Medication appropriateness · older people (aged 65 years or older) living in care homes

1 finding from 1 review

Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1566 participants
Low

Intervention not reported

Medicine costs · older people (aged 65 years or older) living in care homes

1 finding from 1 review

Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 4734 participants
Very low

Summary of findings: Any alternative model of care vs usual care

ED visits · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)

Summary of findings: Any alternative model of care showed no clear difference in emergency department (ED) visits: proportion of residents with at… compared with usual care (low certainty).

1 finding from 1 review

Models for delivery and co‐ordination of primary or secondary health care (or both) to older adults living in aged… 2024 · Cochrane Headline outcomes only
RR 1.01 [0.84, 1.2]
7 studies · 1276 participants
Low