Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

754 questions · 769 findings · 35 reviews · Kidney and Transplant

No studies found 228 · 29.6%GRADE not reported 3 · 0.4%Very low 215 · 28%Low 245 · 31.9%Moderate 74 · 9.6%High 4 · 0.5%

Calcineurin inhibitors ± oral steroids vs oral steroids alone

Complete remission · minimal change disease in adults with nephrotic syndrome

Calcineurin inhibitors ± oral steroids showed no clear difference in complete remission Time frame: 2 to 6 months compared with oral steroids alone (moderate certainty).

1 finding from 1 review

Calcineurin inhibitors ± oral steroids vs oral steroids alone

Complete or partial remission · minimal change disease in adults with nephrotic syndrome

Calcineurin inhibitors ± oral steroids showed no clear difference in complete or partial remission time frame: 3 to 6 months compared with oral steroids alone (moderate certainty).

1 finding from 1 review