Laxative plus bulking agent vs laxative alone
Pain or straining on defecation · postpartum women who underwent surgical repair of third degree perineal tears
1 finding from 1 review
- no estimate extracted1 study · 147 participantsVery low
Findings
What do systematic reviews say?
472 questions · 500 findings · 31 reviews · Pregnancy and Childbirth
No studies found 126 · 25.2%GRADE not reported 48 · 9.6%Very low 105 · 21%Low 135 · 27%Moderate 63 · 12.6%High 23 · 4.6%
Laxative plus bulking agent vs laxative alone
Incidence of postpartum constipation · postpartum women who underwent surgical repair of third degree perineal tears
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Laxative plus bulking agent vs laxative alone
Quality of life · postpartum women who underwent surgical repair of third degree perineal tears
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Laxative plus bulking agent vs laxative alone
Time from completion of operation to first bowel movement (hours) · postpartum women who underwent surgical repair of third degree perineal tears
1 finding from 1 review
- no estimate extracted1 study · 147 participantsVery low
Laxative plus bulking agent vs laxative alone
Adverse effects on women: faecal incontinence during first 10 postpartum days · postpartum women who underwent surgical repair of third degree perineal tears
It is very uncertain whether laxative plus bulking agent changes adverse effects on women: faecal incontinence during first 10… compared with laxative alone (very low certainty).
1 finding from 1 review
- RR 1.81 [1.01, 3.23]1 study · 147 participantsVery low
Laxative plus bulking agent vs laxative alone
Adverse effects on babies · postpartum women who underwent surgical repair of third degree perineal tears
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Laxative vs placebo
Incidence of postpartum constipation · women in the postpartum period
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Laxative vs placebo
Quality of life · women in the postpartum period
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Laxative vs placebo
Time to first BM (№ women with 1st BM on day 1 after delivery) · women in the postpartum period
Laxative may leads to higher time to first bowel movement (BM) (№ women with 1st BM less than 24… compared with placebo (low certainty).
2 findings from 1 review
- RR 2.9 [2.24, 3.75]1 study · 471 participantsLow
- RR 0.94 [0.72, 1.22]1 study · 471 participantsVery low
Laxative vs placebo
Time to first BM (№ women with 1st BM on day 2 after delivery) · women in the postpartum period
Laxative may leads to lower time to first BM (№ women with 1st BM on day 2 after delivery) compared with placebo (low certainty).
3 findings from 1 review
- RR 0.23 [0.11, 0.45]1 study · 471 participantsLow
- RR 0.05 [0, 0.89]1 study · 471 participantsLow
- RR 0.22 [0.03, 1.87]1 study · 471 participantsVery low
Laxative vs placebo
Adverse effects on women: abdominal cramps · women in the postpartum period
Laxative may leads to higher adverse effects on women: abdominal cramps compared with placebo (low certainty).
1 finding from 1 review
- RR 4.23 [1.75, 10.19]1 study · 471 participantsLow
External uterine compression (all methods) plus normal care vs normal care
Mortality due to bleeding ‐ not reported · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601
The review found no eligible studies for this question.
1 finding from 1 review
- Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
One uterine devascularisation technique (uterine arterial embolisation) vs another uterine devascularisation technique (surgical devascularisation plus B‐Lynch)
Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · treating primary postpartum haemorrhage
The review found no eligible studies for this question.
1 finding from 1 review
- Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
One uterine devascularisation technique (uterine arterial embolisation) vs another uterine devascularisation technique (surgical devascularisation plus B‐Lynch)
Number of women with total blood loss 1000 mL or more after randomisation · treating primary postpartum haemorrhage
The review found no eligible studies for this question.
1 finding from 1 review
- Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
One uterine devascularisation technique (uterine arterial embolisation) vs another uterine devascularisation technique (surgical devascularisation plus B‐Lynch)
Mean blood loss (mL) (trialist defined) · treating primary postpartum haemorrhage
The review found no eligible studies for this question.
1 finding from 1 review
- Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
One uterine devascularisation technique (uterine arterial embolisation) vs another uterine devascularisation technique (surgical devascularisation plus B‐Lynch)
Blood transfusion (red cell or whole blood) · treating primary postpartum haemorrhage
The review found no eligible studies for this question.
1 finding from 1 review
- Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
One uterine devascularisation technique (uterine arterial embolisation) vs another uterine devascularisation technique (surgical devascularisation plus B‐Lynch)
Side effects of the intervention (e.g. trauma, necrosis) · treating primary postpartum haemorrhage
It is very uncertain whether one uterine devascularisation technique (uterine arterial… changes side effects of the intervention (e.g. trauma, necrosis) compared with another uterine devascularisation technique (surgical… (very low certainty).
1 finding from 1 review
- Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes onlyRR 1.09 [0.08, 15.41]1 study · 23 participantsVery low
Intrauterine balloon tamponade plus normal care (misoprostol) vs normal care (misoprostol)
Mortality due to bleeding · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
It is very uncertain whether intrauterine balloon tamponade plus normal care (misoprostol) changes mortality due to bleeding compared with normal care (misoprostol) (very low certainty).
1 finding from 1 review
- Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes onlyRR 6.21 [0.77, 49.98]1 study · 116 participantsVery low
Intrauterine balloon tamponade plus normal care (misoprostol) vs normal care (misoprostol)
Hysterectomy to control bleeding · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
It is very uncertain whether intrauterine balloon tamponade plus normal care (misoprostol) changes hysterectomy to control bleeding compared with normal care (misoprostol) (very low certainty).
1 finding from 1 review
- Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes onlyRR 4.14 [0.48, 35.93]1 study · 116 participantsVery low
Intrauterine balloon tamponade plus normal care (misoprostol) vs normal care (misoprostol)
Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women diagnosed with primary PPH following vaginal birth. Women were suspected to have PPH due to clinical atony and who were quote:…
The review found no eligible studies for this question.
1 finding from 1 review
- Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found