Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,447 questions · 2,590 findings · 266 reviews

No studies found 699 · 27%GRADE not reported 289 · 11.2%Very low 614 · 23.7%Low 605 · 23.4%Moderate 322 · 12.4%High 61 · 2.4%

Active body surface warming systems vs control

Major cardiovascular complications (cardiovascular death, non‐fatal myocardial infarction, non‐fatal stroke, and non‐fatal cardiac arrest) · adults undergoing surgery

Active body surface warming systems showed no clear difference in major cardiovascular complications (cardiovascular death, non‐fatal… compared with control (low certainty).

1 finding from 1 review

ACTIVA bioactive restorative material vs Glass ionomer cement (GIC)

Secondary caries · Patients requiring dental restoration; permanent teeth

Over 1 year in permanent teeth, the effect of ACTIVA versus GIC on secondary caries is very uncertain (RR 22.80, 95% CI 0.89-584.17; very low certainty).

1 finding from 1 review

Higher JIA disease activity/severity (e.g., high JADAS/activity scores, polyarticular RF-negative subtype, active disease, anti-TNFalpha or cyclosporine medication) vs Lower JIA disease activity / inactive or milder JIA

Prevalence and severity of oral and TMJ diseases/conditions (periodontal status and dental caries) · Children and adolescents with juvenile idiopathic arthritis (JIA)

Some studies suggested greater JIA disease activity/severity (and certain medications) was associated with worse periodontal and caries outcomes, but small samples meant no solid conclusion could be drawn (ungraded).

1 finding from 1 review

Alternating pressure (active) air surfaces vs foam surfaces

Proportion of participants developing a new pressure ulcer · pressure ulcer prevention

Alternating pressure (active) air surfaces showed no clear difference in proportion of participants developing a new pressure ulcer compared with foam surfaces (low certainty).

1 finding from 1 review

Active treatment vs observation

Eradication of MRSA · adults or children with positive microbiological isolate of MRSA from a respiratory tract specimen

Active treatment showed no clear difference in eradication of MRSA: number of participants that were MRSA‐negativea compared with observation only (low certainty).

1 finding from 1 review

Active treatment vs observation

Time until next positive MRSA isolate (from clinically relevant respiratory culture) · adults or children with positive microbiological isolate of MRSA from a respiratory tract specimen

The review found no eligible studies for this question.

1 finding from 1 review