Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,545 questions · 2,661 findings · 317 reviews

No studies found 608 · 22.8%GRADE not reported 505 · 19%Very low 695 · 26.1%Low 540 · 20.3%Moderate 249 · 9.4%High 64 · 2.4%

Nanocrystalline hydroxyapatite (Ostim) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis

Nanocrystalline hydroxyapatite (Ostim) led to lower change in probing attachment level (PAL) compared with bovine-derived xenograft (Bio-Oss) plus resorbable barrier; GRADE not reported.

1 finding from 1 review

Nutritional supplement (500ml) and standard diet vs standard diet

Mortality during time on waiting list (ITT) · adult patients before and after liver transplantation.

It is very uncertain whether nutritional supplement (500ml) and standard diet changes mortality during time on waiting list (ITT) compared with standard diet alone (very low certainty).

1 finding from 1 review

Nutritional supplement (500ml) and standard diet vs standard diet

Six months mortality after liver transplantation (ITT) · adult patients before and after liver transplantation.

It is very uncertain whether nutritional supplement (500ml) and standard diet changes six months mortality after liver transplantation (ITT) compared with standard diet alone (very low certainty).

1 finding from 1 review

Nutritional supplement (500ml) and standard diet vs standard diet

Mild acute rejection episodes (within 6 months after LTx) · adult patients before and after liver transplantation.

It is very uncertain whether nutritional supplement (500ml) and standard diet changes mild acute rejection episodes (within 6 months after LTx) compared with standard diet alone (very low certainty).

1 finding from 1 review

Nutritional supplement (500ml) and standard diet vs standard diet

Severe acute rejection episodes (within six months after LTx) · adult patients before and after liver transplantation.

It is very uncertain whether nutritional supplement (500ml) and standard diet changes severe acute rejection episodes (within six months after LTx) compared with standard diet alone (very low certainty).

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Complications and side effects · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement led to lower complications and side effects compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Recurrence of peri-implantitis · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement showed no clear difference in recurrence of peri-implantitis compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement showed no clear difference in change in probing pocket depth (PPD) compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Nanocrystalline hydroxyapatite (Ostim) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Change in gingival recession (REC) · People with at least one dental implant affected by perimplantitis

Nanocrystalline hydroxyapatite (Ostim) showed no clear difference in change in gingival recession (REC) compared with bovine-derived xenograft (Bio-Oss) plus resorbable barrier; GRADE not reported.

1 finding from 1 review

Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox) added to manual debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis

Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox)… led to higher change in probing pocket depth (PPD) compared with manual debridement with chlorhexidine (no antibiotic); GRADE not reported.

1 finding from 1 review

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Reported pain (mm on VAS) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

Intra-articular injection of sodium hyaluronate led to lower reported pain (mm on VAS) compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

1 finding from 1 review

Nanocrystalline hydroxyapatite (Ostim) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Recurrence of peri-implantitis · People with at least one dental implant affected by perimplantitis

Nanocrystalline hydroxyapatite (Ostim) showed no clear difference in recurrence of peri-implantitis compared with bovine-derived xenograft (Bio-Oss) plus resorbable barrier; GRADE not reported.

1 finding from 1 review