Findings

What do systematic reviews say?

4,587 questions · 5,761 findings · 495 reviews

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No studies found 1,011 · 17.5%GRADE not reported 1,797 · 31.2%Very low 1,100 · 19.1%Low 1,052 · 18.3%Moderate 649 · 11.3%High 152 · 2.6%

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Intervention not reported

Adverse effects (1 day) · adults over the age of 50 with a unilateral transfemoral amputation

The review found no eligible studies for this question.

1 finding from 1 review

Prosthetic rehabilitation for older dysvascular people following a unilateral transfemoral amputation 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mesh vs non‐mesh repair

Hernia recurrence · adults undergoing inguinal and femoral hernia repair

Mesh probably leads to lower hernia recurrence compared with non‐mesh repair (moderate certainty).

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
RR 0.46 [0.26, 0.8]
21 studies · 5575 participants
Moderate

Mesh vs non‐mesh repair

Surgical complications ‐ neurovascular or visceral injury · adults undergoing inguinal and femoral hernia repair

Mesh leads to lower surgical complications ‐ neurovascular or visceral injury compared with non‐mesh repair (high certainty).

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
RR 0.61 [0.49, 0.76]
24 studies · 6293 participants
High

Mesh vs non‐mesh repair

Surgical complications ‐ wound infection · adults undergoing inguinal and femoral hernia repair

Mesh showed no clear difference in surgical complications ‐ wound infection compared with non‐mesh repair (low certainty).

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
RR 1.29 [0.89, 1.86]
21 studies · 4540 participants
Low

Mesh vs non‐mesh repair

Wound dehiscence · adults undergoing inguinal and femoral hernia repair

Mesh showed no clear difference in surgical complications ‐ wound dehiscence compared with non‐mesh repair (low certainty).

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
RR 0.55 [0.12, 2.48]
2 studies · 329 participants
Low

Mesh vs non‐mesh repair

Mortality (within 30 days post‐surgery) · adults undergoing inguinal and femoral hernia repair

The review found no eligible studies for this question.

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mesh vs non‐mesh repair

Operating time · adults undergoing inguinal and femoral hernia repair

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 4148 participants
Very low

Mesh vs non‐mesh repair

Length of postoperative hospital stay · adults undergoing inguinal and femoral hernia repair

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 2966 participants
Low

Mesh vs non‐mesh repair

Time to return to full ADLs (days) · adults undergoing inguinal and femoral hernia repair

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 3183 participants
Low

Mesh vs non‐mesh repair

Conversion to open surgery · adults undergoing inguinal and femoral hernia repair

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1680 participants
Low

Transradial vs transfemoral approach

Short‐term NACE · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial probably leads to lower short‐term NACE compared with transfemoral approach (moderate certainty).

1 finding from 1 review

Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in… 2018 · Cochrane Headline outcomes only
RR 0.76 [0.61, 0.94]
4 studies · 17133 participants
Moderate

Transradial vs transfemoral approach

Short‐term cardiac death · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial probably leads to lower short‐term cardiac death compared with transfemoral approach (moderate certainty).

1 finding from 1 review

Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in… 2018 · Cochrane Headline outcomes only
RR 0.69 [0.54, 0.88]
11 studies · 11170 participants
Moderate

Transradial vs transfemoral approach

Short‐term MI · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial showed no clear difference in short‐term MI compared with transfemoral approach (high certainty).

1 finding from 1 review

Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in… 2018 · Cochrane Headline outcomes only
RR 0.91 [0.81, 1.02]
11 studies · 19430 participants
High

Transradial vs transfemoral approach

Success of the procedure · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial probably leads to lower success of the procedure compared with transfemoral approach (moderate certainty).

1 finding from 1 review

Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in… 2018 · Cochrane Headline outcomes only
RR 0.97 [0.96, 0.98]
28 studies · 25920 participants
Moderate

Transradial vs transfemoral approach

Short‐term all‐cause mortality · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial leads to lower short‐term all‐cause mortality compared with transfemoral approach (high certainty).

1 finding from 1 review

Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in… 2018 · Cochrane Headline outcomes only
RR 0.77 [0.62, 0.95]
10 studies · 18955 participants
High

Transradial vs transfemoral approach

Bleeding · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial may leads to lower bleeding compared with transfemoral approach (low certainty).

1 finding from 1 review

Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in… 2018 · Cochrane Headline outcomes only
RR 0.54 [0.4, 0.74]
20 studies · 23043 participants
Low

Transradial vs transfemoral approach

Access site complications · people with coronary artery disease undergoing diagnostic coronary angiography and percutaneous coronary intervention

Transradial may leads to lower access site complications compared with transfemoral approach (low certainty).

1 finding from 1 review

Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in… 2018 · Cochrane Headline outcomes only
RR 0.36 [0.22, 0.59]
24 studies · 16112 participants
Low

Intramuscular corticosteroids vs oral corticosteroid

Relapse · patients with acute asthma

Intramuscular corticosteroids showed no clear difference in relapse compared with oral corticosteroids (low certainty).

3 findings from 1 review

Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
RR 0.94 [0.72, 1.24]
9 studies · 804 participants
Low
Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
RR 0.74 [0.51, 1.07]
7 studies · 742 participants
Moderate
Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
RR 0.99 [0.74, 1.33]
5 studies · 556 participants
Low

Intramuscular corticosteroids vs oral corticosteroid

Adverse events · patients with acute asthma

Intramuscular corticosteroids showed no clear difference in adverse events compared with oral corticosteroids (low certainty).

1 finding from 1 review

Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
RR 0.83 [0.64, 1.07]
5 studies · 404 participants
Low

Intramuscular corticosteroids vs oral corticosteroid

Health outcomes Peak expiratory flow readings (higher readings indicate better peak flow) · patients with acute asthma

1 finding from 1 review

Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for… 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 272 participants
Moderate