Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,752 questions · 6,648 findings · 688 reviews

No studies found 1,125 · 16.9%GRADE not reported 670 · 10.1%Very low 1,796 · 27%Low 1,685 · 25.3%Moderate 1,075 · 16.2%High 297 · 4.5%

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Intervention not reported

Overall survival · women with stage I endometrial cancer

The intervention showed no clear difference in overall survival (moderate certainty).

1 finding from 1 review

Intervention not reported

Recurrence‐free survival · women with stage I endometrial cancer

The intervention showed no clear difference in recurrence‐free survival (moderate certainty).

1 finding from 1 review

Intervention not reported

Direct surgical morbidity · women with stage I endometrial cancer

The intervention showed no clear difference in direct surgical morbidity (moderate certainty).

1 finding from 1 review

Intervention not reported

Surgery‐related systemic morbidity · women with stage I endometrial cancer

The intervention probably leads to higher surgery‐related systemic morbidity (moderate certainty).

1 finding from 1 review

Intervention not reported

Lymphoedema or lymphocyst · women with stage I endometrial cancer

The intervention leads to higher lymphoedema or lymphocyst (high certainty).

1 finding from 1 review

Gestrinone vs danazol

Side effects ‐ hot flushes · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes side effects: hot flushes compared with danazol (very low certainty).

1 finding from 1 review

Gestrinone vs leuprolin

Percentage days bleeding or spotting (questionnaire) · women with symptomatic endometriosis

Gestrinone may leads to higher spotting or bleeding compared with leuprolin (low certainty).

1 finding from 1 review

Gestrinone vs danazol

Pelvic pain · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes pelvic pain: none or mild compared with danazol (very low certainty).

1 finding from 1 review

Gestrinone vs danazol

Dysmenorrhoea: none or mild · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes dysmenorrhoea: none or mild compared with danazol (very low certainty).

1 finding from 1 review

Gestrinone vs danazol

Dyspareunia: none or mild · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes dyspareunia: none or mild compared with danazol (very low certainty).

1 finding from 1 review