Lack of efficacy withdrawal · adults with painful diabetic neuropathy
Topical clonidine (TC) showed no clear difference in withdrawal due to lack of efficacy (12 weeks) compared with placebo (low certainty).
1 finding from 1 review
Adverse events · pharmaceutical opioid dependent people
It is very uncertain whether full or partial opioid agonist maintenance changes adverse events compared with placebo, detoxification only or psychological treatment… (very low certainty).
1 finding from 1 review
Days of unsanctioned opioid use · pharmaceutical opioid dependent people
Full or partial opioid agonist maintenance showed no clear difference in days of unsanctioned opioid use (as number of days/30 or days/7) compared with placebo, detoxification only or psychological treatment… (low certainty).
1 finding from 1 review
Opioid use · pharmaceutical opioid dependent people
It is very uncertain whether full or partial opioid agonist maintenance changes self‐reported opioid use at treatment completion compared with placebo, detoxification only or psychological treatment… (very low certainty).
2 findings from 1 review
Retention in treatment · pharmaceutical opioid dependent people
Full or partial opioid agonist maintenance probably leads to higher retention: proportion of participants retained in treatment compared with placebo, detoxification only or psychological treatment… (moderate certainty).
1 finding from 1 review
Fatigue –concentration problems Subscale from CIS · people with a primary brain tumour
1 finding from 1 review
Cognition Semantic Fluency · people with a primary brain tumour
1 finding from 1 review
Cognition Lexical Fluency · people with a primary brain tumour
1 finding from 1 review
Cognitive subdomain: episodic memory measured at the end of · people with a primary brain tumour
1 finding from 1 review
Cognitive function · people with a primary brain tumour
1 finding from 1 review
Affectivity Norris Scale · people with a primary brain tumour
1 finding from 1 review
Apathy Marin Scale · people with a primary brain tumour
1 finding from 1 review
Depressive symptoms · people with a primary brain tumour
1 finding from 1 review
Health‐related quality of life European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ‐C30). Scale from: 0 to 100 (a higher score means a better outcome) · people with a primary brain tumour
1 finding from 1 review
Quality of life EORTC QLQ‐BN 20 · people with a primary brain tumour
1 finding from 1 review
Fatigue · people with a primary brain tumour
1 finding from 1 review
Fatigue –reduced motivation Subscale from CIS · people with a primary brain tumour
1 finding from 1 review
Cognition Symbol Digit Modalities Test (median (range)) · people with a primary brain tumour
1 finding from 1 review
Quality of life, self‐rated at post‐treatment · people with a primary brain tumour
1 finding from 1 review
Adverse events (grade ≥ 3) · people with a primary brain tumour
1 finding from 1 review