Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only

No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%

Intervention not reported

Primary outcome 1: participant‐ or parent‐rated symptoms of eczema (SCORAD part C) at the end of active treatment Visual analogue scale for itch and sleep disturbance ranging from 0 to 10 for each symptom and combined ranging from 0 to 20. The hig... · male and female patients 0 to 55 years of age with physician‐diagnosed eczema
1 finding from 1 review

Intervention not reported

Primary outcome 1: participant‐ or parent‐rated global change in eczema symptoms at the end of active treatment (binary outcome) Change in risk for worsened/unchanged eczema Duration of · male and female patients 0 to 55 years of age with physician‐diagnosed eczema

The intervention showed no clear difference in primary outcome 1: participant‐ or parent‐rated global change in… (low certainty).

1 finding from 1 review

Intervention not reported

Primary outcome 2: participant‐ or parent‐rated participant quality of life score at the end of active treatment Scales used: DLQI, IDQoL, Skindex‐29, CDLQI. On those scales, the higher the score, the more severely the quality of life is affected ... · male and female patients 0 to 55 years of age with physician‐diagnosed eczema
1 finding from 1 review

Intervention not reported

Primary outcome 2: participant‐ or parent‐rated family quality of life score at the end of active treatment Scale used: DFI, FDLQI. On those scales, the higher the score, the more severely the quality of life is affected Duration of · male and female patients 0 to 55 years of age with physician‐diagnosed eczema
1 finding from 1 review

Intervention not reported

Secondary outcome 4: global eczema severity score (total SCORAD) at the end of active treatment (Investigator‐rated eczema severity) Scale used: total SCORAD ranging from 0 to 103. The higher the score, the more severe the disease Duration of · male and female patients 0 to 55 years of age with physician‐diagnosed eczema
1 finding from 1 review

Intervention not reported

Secondary outcome 6: adverse events (gastrointestinal symptoms) during active treatment Duration of · male and female patients 0 to 55 years of age with physician‐diagnosed eczema

The intervention showed no clear difference in secondary outcome 6: adverse events (gastrointestinal symptoms)… (low certainty).

1 finding from 1 review

Intervention not reported

Primary outcomes · children aged 4 to 12 years with CAS of unknown cause

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Accuracy of production on treated items Measured by: counting the number of real words produced correctly (/x) · children aged 4 to 12 years with CAS of unknown cause
1 finding from 1 review

Intervention not reported

Accuracy of production on non‐treated items Measured by: counting the number of real words produced correctly (/x) · children aged 4 to 12 years with CAS of unknown cause
1 finding from 1 review

Intervention not reported

Secondary outcomes · children aged 4 to 12 years with CAS of unknown cause

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Speech production consistency Measured by: calculating the number of inconsistent productions of 25 words produced 3 times using the DEAP inconsistency subtestb · children aged 4 to 12 years with CAS of unknown cause
1 finding from 1 review

Intervention not reported

Accuracy of connected speech Measured by: counting the number of correct imitations of 3 word phrases (/x) · children aged 4 to 12 years with CAS of unknown cause
1 finding from 1 review