Findings

What do systematic reviews say?

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

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No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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Dexamethasone vs betamethasone – child outcomes

Necrotising enterocolitis · women at risk of preterm birth

Dexamethasone showed no clear difference in necrotising enterocolitis compared with betamethasone – fetal/neonatal outcomes (low certainty).

1 finding from 1 review

Different corticosteroids and regimens for accelerating fetal lung maturation for babies at risk of preterm birth 2022 · Cochrane Headline outcomes only
RR 5.08 [0.25, 105.15]
2 studies · 441 participants
Low

Conjugated oral oestrogens vs transdermal 17ß‐estradiol

Uterine volume (cm³) · girls with Turner syndrome who were treated with prepubertal growth hormone

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Oral vs vaginal administration of oestradiol and dydrogesterone

Uterine volume (cm³) · women with premature ovarian insufficiency (POI) awaiting oocyte donation

2 findings from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Oral vs vaginal administration of oestradiol and dydrogesterone

Endometrial thickness (mm) · women with premature ovarian insufficiency (POI) awaiting oocyte donation

2 findings from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low
Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Oral vs vaginal administration of oestradiol and dydrogesterone

Endometrial histology · women with premature ovarian insufficiency (POI) awaiting oocyte donation

The review found no eligible studies for this question.

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral vs vaginal administration of oestradiol and dydrogesterone

Uterine perfusion · women with premature ovarian insufficiency (POI) awaiting oocyte donation

The review found no eligible studies for this question.

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Conjugated oral oestrogens vs transdermal 17ß‐estradiol

Endometrial thickness (mm) · girls with Turner syndrome who were treated with prepubertal growth hormone

The review found no eligible studies for this question.

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral vs vaginal administration of oestradiol and dydrogesterone

Reproductive outcomes · women with premature ovarian insufficiency (POI) awaiting oocyte donation

The review found no eligible studies for this question.

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral vs vaginal administration of oestradiol and dydrogesterone

Adverse events · women with premature ovarian insufficiency (POI) awaiting oocyte donation

The review found no eligible studies for this question.

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Conjugated oral oestrogens vs transdermal 17ß‐estradiol

Endometrial histology · girls with Turner syndrome who were treated with prepubertal growth hormone

The review found no eligible studies for this question.

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Conjugated oral oestrogens vs transdermal 17ß‐estradiol

Uterine perfusion · girls with Turner syndrome who were treated with prepubertal growth hormone

The review found no eligible studies for this question.

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Conjugated oral oestrogens vs transdermal 17ß‐estradiol

Reproductive outcomes · girls with Turner syndrome who were treated with prepubertal growth hormone

The review found no eligible studies for this question.

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Conjugated oral oestrogens vs transdermal 17ß‐estradiol

Adverse events · girls with Turner syndrome who were treated with prepubertal growth hormone

The review found no eligible studies for this question.

1 finding from 1 review

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Supportive and counselling interventions vs treatment

Anxiety · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Supportive and counselling interventions vs treatment

Quality of life post‐treatment · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 935 participants
Moderate

Supportive and counselling interventions vs treatment

Activities of daily living · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 511 participants
Very low

Supportive and counselling interventions vs treatment

Cognitive function · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 730 participants
Low

Supportive and counselling interventions vs treatment

Neuropsychiatric symptoms · depression and anxiety for people with dementia

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 538 participants
Very low

CBT vs treatment

Anxiety · depression and anxiety for people with dementia and MCI

It is very uncertain whether CBT treatments changes anxiety symptoms post‐treatment compared with treatment (very low certainty).

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
SMD 0.03
3 studies · 143 participants
Very low

CBT vs treatment

Quality of life post‐treatment · depression and anxiety for people with dementia and MCI

CBT treatments showed no clear difference in quality of life post‐treatment compared with treatment (moderate certainty).

1 finding from 1 review

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment 2022 · Cochrane Headline outcomes only
SMD 0.31
7 studies · 459 participants
Moderate