Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.
FOLFIRI + targeted therapy probably leads to higher severe adverse effects compared with FOLFIRI (moderate certainty).
It is very uncertain whether FOLFOX + targeted therapy changes overall survival compared with FOLFOX (very low certainty).
FOLFOX + targeted therapy may leads to lower progression‐free survival compared with FOLFOX (low certainty).
FOLFOX + targeted therapy probably leads to higher overall tumour response compared with FOLFOX (moderate certainty).
FOLFOX + targeted therapy leads to higher severe adverse effects compared with FOLFOX (high certainty).
Irinotecan + targeted therapy showed no clear difference in overall survival compared with irinotecan (low certainty).
Modern chemotherapy regimens leads to higher overall tumour response compared with 5‐flourouracil (high certainty).
Irinotecan + targeted therapy probably leads to lower progression‐free survival compared with irinotecan (moderate certainty).
Irinotecan + targeted therapy leads to higher overall tumour response compared with irinotecan (high certainty).
Irinotecan + targeted therapy leads to higher severe adverse effects compared with irinotecan (high certainty).
Modern chemotherapy regimens probably leads to higher severe adverse effects compared with 5‐flourouracil (moderate certainty).
Chemotherapy + bevacizumab leads to lower overall survival compared with chemotherapy (high certainty).
Chemotherapy + bevacizumab leads to lower progression‐free survival compared with chemotherapy (high certainty).
Chemotherapy + bevacizumab leads to higher overall tumour response compared with chemotherapy (high certainty).
Chemotherapy + bevacizumab showed no clear difference in severe adverse effects compared with chemotherapy (low certainty).
Irinotecan‐based regimens probably leads to lower progression‐free survival compared with irinotecan (moderate certainty).
The intervention leads to lower progression‐free survival (high certainty).
The intervention showed no clear difference in overall survival (high certainty).
The intervention showed no clear difference in tumour response rate (high certainty).
It is very uncertain whether the intervention changes overall grade 3 to 4 toxicity (very low certainty).