What do systematic reviews say?

TDF vs placebo

TDF probably leads to lower HIV infection compared with placebo (moderate certainty).

• Antiretroviral pre‐exposure prophylaxis (PrEP) for preventing HIV in high‐risk individuals 2012 · Cochrane Headline outcomes only
  RR 0.33 [0.2, 0.55]
  2 studies · 4027 participants
  Moderate

TDF vs placebo

TDF showed no clear difference in serious adverse events compared with placebo (moderate certainty).

• Antiretroviral pre‐exposure prophylaxis (PrEP) for preventing HIV in high‐risk individuals 2012 · Cochrane Headline outcomes only
  RR 1.03 [0.79, 1.33]
  1 study · 3168 participants
  Moderate

Transfer from incubator to cot at lower vs higher body weight

• Transfer of preterm infants from incubator to open cot at lower versus higher body weight 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 276 participants
  High

Transfer from incubator to cot at lower vs higher body weight

Transfer from incubator to cot at lower showed no clear difference in proportion of infants having at least one episode of low temperature… compared with higher body weight (high certainty).

• Transfer of preterm infants from incubator to open cot at lower versus higher body weight 2011 · Cochrane Headline outcomes only
  RR 1.43 [0.78, 2.62]
  2 studies · 276 participants
  High

Transfer from incubator to cot at lower vs higher body weight

Transfer from incubator to cot at lower showed no clear difference in proportion of infants having at least one episode of returning to… compared with higher body weight (moderate certainty).

• Transfer of preterm infants from incubator to open cot at lower versus higher body weight 2011 · Cochrane Headline outcomes only
  RR 1.78 [0.77, 4.08]
  3 studies · 336 participants
  Moderate

Transfer from incubator to cot at lower vs higher body weight

• Transfer of preterm infants from incubator to open cot at lower versus higher body weight 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 276 participants
  High

Transfer from incubator to cot at lower vs higher body weight

• Transfer of preterm infants from incubator to open cot at lower versus higher body weight 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 276 participants
  High

Transfer from incubator to cot at lower vs higher body weight

• Transfer of preterm infants from incubator to open cot at lower versus higher body weight 2011 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 276 participants
  High

Transfer from incubator to cot at lower vs higher body weight

Transfer from incubator to cot at lower showed no clear difference in proportion of infants exclusive breastfeeding at discharge compared with higher body weight (high certainty).

• Transfer of preterm infants from incubator to open cot at lower versus higher body weight 2011 · Cochrane Headline outcomes only
  RR 1 [0.81, 1.24]
  2 studies · 276 participants
  High

iMRI image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Neuronavigation image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Neuronavigation image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Neuronavigation image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

iMRI image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

iMRI image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

iMRI image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

5‐ALA image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

5‐ALA image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

5‐ALA image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

5‐ALA image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found