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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Brushed less than twice per day vs Brushed twice or more per day

Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years

It is very uncertain whether brushed less than twice per day changes fluorosis (percentage prevalence in permanent teeth) compared with brushed twice or more per day (very low certainty).

2 findings from 1 review

Silver diamine fluoride (SDF) plus fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Dietary advice on how to achieve a healthy diet for infants (tailored advice focused on a diet low in saturated fat and cholesterol intake) vs usual care

Mother plaque (sub- and supragingival calculus) · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

Dietary advice on how to achieve a healthy diet for infants… showed no clear difference in mother plaque (sub- and supragingival calculus) compared with standard care; GRADE not reported.

1 finding from 1 review

Silver diamine fluoride (SDF) vs Restoration (restorative treatment)

Caries arrest · Children and adults (with or without carious lesions)

It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with restoration (restorative treatment) (very low certainty).

1 finding from 1 review

Silver diamine fluoride (SDF) vs Glass ionomer cement (GIC) plus fluoride varnish

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Occlusal splint vs No treatment or placebo (non-occlusal or transparent-foil placebo splint)

Severity of joint noise · People with temporomandibular disorders (TMD)

It is very uncertain whether occlusal splint changes severity of joint noise compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).

1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Pushing Splints

ANB (ANPog) · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) led to higher ANB (ANPog) compared with pushing Splints; GRADE not reported.

1 finding from 1 review

Silver diamine fluoride (SDF) vs Atraumatic restorative treatment (ART) with glass ionomer cement (GIC) or glass ionomer material

Primary caries prevention · Children and adults (with or without carious lesions)

The review found no eligible studies for this question.

1 finding from 1 review

Silver diamine fluoride (SDF) vs Silver nitrate plus fluoride varnish

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Facemask with rapid maxillary expansion (RME) vs Facemask with alternating rapid maxillary expansion and constriction (Alt-RAMEC)

Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask with rapid maxillary expansion (RME) showed no clear difference in wits appraisal compared with facemask with alternating rapid maxillary expansion and constriction…; GRADE not reported.

1 finding from 1 review

Jaw opening exercises alone vs Ultrasound plus jaw opening exercises

Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

It is very uncertain whether jaw opening exercises alone changes maximal mouth opening (interincisal distance) compared with ultrasound plus jaw opening exercises (very low certainty).

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Participant satisfaction or quality of life · People with temporomandibular disorders (TMD)

Occlusal splint led to lower participant satisfaction or quality of life compared with physical therapy (ultrasound, exercise, sensorimotor training,…; GRADE not reported.

1 finding from 1 review

Occlusal splint vs acupuncture

Participant satisfaction or quality of life · People with temporomandibular disorders (TMD)

Occlusal splint showed no clear difference in participant satisfaction or quality of life compared with acupuncture; GRADE not reported.

1 finding from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT

Change in probing pocket depth (PPD) · Adults (> 18 years) with peri-implant mucositis, receiving active treatment

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… showed no clear difference in change in probing depth (PD/PPD) compared with submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT; GRADE not reported.

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Muscle pain when chewing · People with temporomandibular disorders (TMD)

It is very uncertain whether occlusal splint changes muscle pain when chewing compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).

1 finding from 1 review

Surgical miniplates with facemask vs Surgical miniplates with Class III elastics

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Surgical miniplates with facemask showed no clear difference in ANB compared with surgical miniplates with Class III elastics; GRADE not reported.

1 finding from 1 review