Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,782 questions · 1,852 findings · 128 reviews · Effective Practice and Organisation of Care

No studies found 557 · 30.1%GRADE not reported 53 · 2.9%Very low 446 · 24.1%Low 476 · 25.7%Moderate 255 · 13.8%High 65 · 3.5%

Intervention not reported

Anthropometric outcomes: median weight gain per day (g/kg/d) Defined as ((discharge weight − admission weight)/weight on admission)/days on treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting
1 finding from 1 review

Intervention not reported

Non‐response to treatment Defined as not meeting the criteria for recovery within 4 months Hussain 2021 · children aged > 6 months and ≤ 5 years with wasting

The intervention may leads to higher non‐response to treatment Defined as not meeting the criteria for… (low certainty).

1 finding from 1 review

Intervention not reported

Transfer to inpatient care Defined as referral for: presence of danger signs and failed appetite test on first day of treatment (Alvarez Moran 2018)b; appearance of severe signs of illness, persistent oedema, absence of weight gain in non‐oedemato... · children aged > 6 months and < 5 years with wasting

It is very uncertain whether the intervention changes transfer to inpatient care Defined as referral for: presence of… (very low certainty).

1 finding from 1 review

Intervention not reported

Treatment coverage Defined as proportion of children with SAM who receive treatment (number of children treated from baseline to endline; Wilunda 2021)e · children aged > 6 months and < 5 years with wasting

It is very uncertain whether the intervention changes treatment coverage Defined as proportion of children with SAM who… (very low certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: number of children with normal or underweight WHZ on discharge Defined as WHZ > −2 (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with normal or… (low certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: number of children with WHZ in moderate wasting range on discharge Defined as WHZ between −3 and −2 (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with WHZ in moderate… (moderate certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: number of children with WHZ in severe wasting range on discharge Defined as WHZ < −3: Hussain 2021 · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with WHZ in severe… (moderate certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: number of children with MUAC ≥ 115 mm on discharge (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in anthropometric outcomes: number of children with MUAC ≥ 115 mm on… (moderate certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: weight gain per day (g/kg/day) Calculated as ((discharge weight − admission weight)/weight on admission)/days in treatment among recovered children (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting
1 finding from 1 review