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What do systematic reviews say?

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Evidence found and GRADE certainty

329 questions · 345 findings · 47 reviews · Headline outcomes only

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No studies found 93 · 27%GRADE not reported 8 · 2.3%Very low 44 · 12.8%Low 118 · 34.2%Moderate 75 · 21.7%High 7 · 2%

Antibiotics vs topical treatments

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Antibiotics showed no clear difference in incidence of mastitis within 6 months postpartum ‐ Antibiotics… compared with topical treatments (low certainty).

2 findings from 1 review

Probiotics vs placebo

Nipple damage within 6 months postpartum · postpartum breastfeeding women

It is very uncertain whether probiotics changes nipple damage within 6 months postpartum compared with placebo (very low certainty).

1 finding from 1 review

Hydrothermally processed cereal with anti‐secretory factor‐inducing properties vs standard cereal standard cereal

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Hydrothermally processed cereal with anti‐secretory factor‐inducing… showed no clear difference in incidence of mastitis within 6 months postpartum compared with standard cereal standard cereal (low certainty).

1 finding from 1 review

Hydrothermally processed cereal with anti‐secretory factor‐inducing properties vs standard cereal standard cereal

Recurrence of mastitis within 12 months postpartum · postpartum breastfeeding women

Hydrothermally processed cereal with anti‐secretory factor‐inducing… showed no clear difference in recurrence of mastitis within 12 months postpartum compared with standard cereal standard cereal (low certainty).

1 finding from 1 review