Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

238 questions · 242 findings · 21 reviews · Headline outcomes only

No studies found 37 · 15.3%GRADE not reported 15 · 6.2%Very low 78 · 32.2%Low 52 · 21.5%Moderate 49 · 20.2%High 11 · 4.5%

QUETIAPINE vs RISPERIDONE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · schizophrenia

QUETIAPINE probably leads to lower adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (moderate certainty).

1 finding from 1 review

QUETIAPINE vs RISPERIDONE

Adverse effects: 3. Metabolic weight gain ≥7% of total body weight · schizophrenia

QUETIAPINE showed no clear difference in adverse effects: 3. Metabolic weight gain ≥7% of total body weight compared with RISPERIDONE (moderate certainty).

1 finding from 1 review