Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,209 questions · 2,322 findings · 227 reviews · Headline outcomes only

No studies found 644 · 27.7%GRADE not reported 135 · 5.8%Very low 591 · 25.5%Low 582 · 25.1%Moderate 309 · 13.3%High 61 · 2.6%

Topical active treatment in combination with moisturiser vs topical active treatment alone

Number of participants reporting an adverse event · people with eczema

It is very uncertain whether topical active treatment in combination with moisturiser changes number of participants reporting an adverse event compared with topical active treatment alone (very low certainty).

1 finding from 1 review

Active body surface warming systems vs control

Major cardiovascular complications (cardiovascular death, non‐fatal myocardial infarction, non‐fatal stroke, and non‐fatal cardiac arrest) · adults undergoing surgery

Active body surface warming systems showed no clear difference in major cardiovascular complications (cardiovascular death, non‐fatal… compared with control (low certainty).

1 finding from 1 review