Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,890 questions · 3,917 findings · 272 reviews · Oral Health

No studies found 429 · 11%GRADE not reported 2,657 · 67.8%Very low 512 · 13.1%Low 219 · 5.6%Moderate 80 · 2%High 20 · 0.5%

Sodium bicarbonate rinse (plus toothbrushing) vs Water rinse (plus toothbrushing)

Incidence of VAP · Critically ill patients receiving mechanical ventilation in ICU

Sodium bicarbonate rinse (plus toothbrushing) showed no clear difference in incidence of VAP compared with water rinse (plus toothbrushing); GRADE not reported.

1 finding from 1 review

Antimicrobial coolant A (chlorhexidine) vs povidone‐iodine

Reduction in level of contamination in aerosols (CFU): chlorhexidine vs povidone iodine coolant during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether antimicrobial coolant A (chlorhexidine) changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with antimicrobial coolant B (povidone iodine) (very low certainty).

1 finding from 1 review

Antimicrobial coolant A (chlorhexidine) vs Antimicrobial coolant B (cinnamon extract)

Reduction in level of contamination in aerosols (CFU): chlorhexidine vs cinnamon extract coolant during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether antimicrobial coolant A (chlorhexidine) changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with antimicrobial coolant B (cinnamon extract) (very low certainty).

1 finding from 1 review

Fluoride varnish vs Fissure sealant (resin-based or glass ionomer)

Caries incidence of occlusal surfaces of first permanent molars · Generally healthy children aged 6 to 9 years with at least one fully erupted first permanent molar with deep fissures or early enamel…

After excluding Bravo 1996, occlusal caries incidence slightly favored fluoride varnish but was not significant, with heterogeneity falling to 0% (RR 0.98, 95% CI 0.82 to 1.16; 3 RCTs; ungraded).

2 findings from 1 review

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) at more than 1 foot from oral cavity (CCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

High-volume evacuation (HVE) led to lower reduction in level of contamination in aerosols (CFU) at more than 1… compared with no HVE; GRADE not reported.

1 finding from 1 review

Cinnamon extract coolant vs Distilled water coolant

Reduction in level of contamination in aerosols (CFU): cinnamon extract coolant vs distilled water during ultrasonic scaling · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether cinnamon extract coolant changes reduction in level of contamination in aerosols (CFU): cinnamon… compared with distilled water coolant (very low certainty).

1 finding from 1 review

Any method, procedure or policy to reduce contaminated aerosols in dental clinics vs Any other method, no treatment or combination of methods

Acceptability and feasibility of the intervention to patients and dentists · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…

The review found no eligible studies for this question.

1 finding from 1 review

Combination system (Isolite) vs Conventional dental suction (low-volume evacuator / saliva ejector)

Reduction in contamination of aerosols (CFU) after ultrasonic scaling / AGP · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether combination system (Isolite) changes reduction in contamination of aerosols (CFU) after ultrasonic… compared with saliva ejector (low-volume evacuator) (very low certainty).

2 findings from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Plaque index (PI) / oral hygiene · Critically ill patients (adults and children) receiving mechanical ventilation in ICU
1 finding from 1 review

Resin-based fissure sealant plus fluoride varnish vs Fluoride varnish

Time taken to apply pit and fissure sealant or fluoride varnish · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review

Rubber dam vs No rubber dam

Reduction in level of contamination in aerosols (CFU) during restorative procedures at 1 metre from mouth (CCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

Rubber dam led to lower reduction in level of contamination in aerosols (CFU) during… compared with no rubber dam; GRADE not reported.

2 findings from 1 review

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) at less than 1 foot from oral cavity (CCTs) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

High-volume evacuation (HVE) showed no clear difference in reduction in level of contamination in aerosols (CFU) at less than 1… compared with no HVE; GRADE not reported.

1 finding from 1 review

High-volume evacuation (HVE) vs No HVE

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling and air polishing at more than 1 foot from oral cavity (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with no HVE (very low certainty).

1 finding from 1 review

Resin-based fissure sealant plus fluoride varnish vs Fluoride varnish

Changes in decayed, missing and filled (DMF) figures at whole-mouth level · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review