Ketogenic diet (KD) vs usual care
Cognition and behaviour · children (aged 1 to 18 years) with drug‐resistant epilepsy
1 finding from 1 review
- no estimate extracted1 study · 57 participantsVery low
Findings
What do systematic reviews say?
4,320 questions · 4,561 findings · 388 reviews
No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%
Ketogenic diet (KD) vs usual care
Quality of life · children (aged 1 to 18 years) with drug‐resistant epilepsy
It is very uncertain whether ketogenic diet (KD) changes quality of life compared with usual care (very low certainty).
1 finding from 1 review
- OR 161 study · 57 participantsVery low
Ketogenic diet (KD) vs usual care
Treatment withdrawal · children (aged 1 to 18 years) with drug‐resistant epilepsy
Ketogenic diet (KD) showed no clear difference in treatment withdrawal compared with usual care (low certainty).
1 finding from 1 review
- RR 1.08 [0.74, 1.57]5 studies · 425 participantsLow
Ketogenic diet (KD) vs usual care
Seizure freedom · adults (aged 16 years and over) with drug‐resistant epilepsy
It is very uncertain whether ketogenic diet (KD) changes seizure freedom compared with usual care (very low certainty).
1 finding from 1 review
- no estimate extracted2 studies · 141 participantsVery low
Ketogenic diet (KD) vs usual care
50% or greater reduction in seizure frequency · adults (aged 16 years and over) with drug‐resistant epilepsy
It is very uncertain whether ketogenic diet (KD) changes 50% or greater reduction in seizure frequency compared with usual care (very low certainty).
1 finding from 1 review
- RR 5.03 [0.26, 97.68]2 studies · 141 participantsVery low
Ketogenic diet (KD) vs usual care
Adverse effects · adults (aged 16 years and over) with drug‐resistant epilepsy
1 finding from 1 review
- no estimate extracted2 studies · 141 participantsVery low
Green tea extract supplementation vs placebo
Prostate cancer incidence · adults (aged at least 18 years)
Green tea extract supplementation showed no clear difference in prostate cancer incidence compared with placebo (low certainty).
1 finding from 1 review
- RR 0.5 [0.18, 1.36]3 studies · 201 participantsLow
Highest vs lowest green tea exposure
Stomach cancer risk (18 studies) · adults (aged at least 18 years)
It is very uncertain whether highest changes stomach cancer risk (18 studies) compared with lowest green tea exposure (very low certainty).
1 finding from 1 review
- RR 0.86 [0.74, 1.01]438595 participantsVery low
Highest vs lowest green tea exposure
Liver cancer risk (6 studies) · adults (aged at least 18 years)
Highest showed no clear difference in liver cancer risk (6 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.88 [0.68, 1.14]198885 participantsLow
Highest vs lowest green tea exposure
Pancreatic cancer risk (9 studies) · adults (aged at least 18 years)
Highest showed no clear difference in pancreatic cancer risk (9 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.88 [0.7, 1.1]326564 participantsLow
Highest vs lowest green tea exposure
Colorectal cancer risk (16 studies) · adults (aged at least 18 years)
Highest may leads to lower colorectal cancer risk (16 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.84 [0.74, 0.96]610295 participantsLow
Highest vs lowest green tea exposure
Colon cancer risk (10 studies) · adults (aged at least 18 years)
Highest may leads to lower colon cancer risk (10 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.89 [0.8, 0.98]389974 participantsLow
Highest vs lowest green tea exposure
Rectal cancer risk (9 studies) · adults (aged at least 18 years)
Highest showed no clear difference in rectal cancer risk (9 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.89 [0.75, 1.05]356851 participantsLow
Highest vs lowest green tea exposure
Lung cancer risk (17 studies) · adults (aged at least 18 years)
It is very uncertain whether highest changes lung cancer risk (17 studies) compared with lowest green tea exposure (very low certainty).
1 finding from 1 review
- RR 0.88 [0.76, 1.02]269565 participantsVery low
Highest vs lowest green tea exposure
Breast cancer risk (14 studies) · adults (aged at least 18 years)
It is very uncertain whether highest changes breast cancer risk (14 studies) compared with lowest green tea exposure (very low certainty).
1 finding from 1 review
- RR 0.88 [0.75, 1.02]250822 participantsVery low
Highest vs lowest green tea exposure
Gynaecological cancer risk (10 studies) · adults (aged at least 18 years)
Highest may leads to lower gynaecological cancer risk (10 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.69 [0.57, 0.83]66738 participantsLow
Highest vs lowest green tea exposure
Endometrial cancer risk (5 studies) · adults (aged at least 18 years)
Highest may leads to lower endometrial cancer risk (5 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.77 [0.65, 0.91]60416 participantsLow
Green tea extract supplementation vs placebo
Gynaecological cancer incidence · adults (aged at least 18 years)
Green tea extract supplementation showed no clear difference in gynaecological cancer incidence compared with placebo (low certainty).
1 finding from 1 review
- RR 1.5 [0.41, 5.48]2 studies · 1157 participantsLow
Highest vs lowest green tea exposure
Ovarian cancer risk (5 studies) · adults (aged at least 18 years)
Highest may leads to lower ovarian cancer risk (5 studies) compared with lowest green tea exposure (low certainty).
1 finding from 1 review
- RR 0.64 [0.45, 0.9]6322 participantsLow
Highest vs lowest green tea exposure
Prostate cancer risk (13 studies) · adults (aged at least 18 years)
It is very uncertain whether highest changes prostate cancer risk (13 studies) compared with lowest green tea exposure (very low certainty).
1 finding from 1 review
- RR 0.73 [0.56, 0.94]127239 participantsVery low