Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,745 questions · 4,389 findings · 203 reviews · Oral Health

No studies found 39 · 0.9%GRADE not reported 3,844 · 87.6%Very low 198 · 4.5%Low 137 · 3.1%Moderate 134 · 3.1%High 37 · 0.8%

Intervention not reported

Dental caries in permanent teeth · Children (permanent dentition) worldwide

In Europe, the pooled prevalence of permanent-teeth caries in children was 44.1% (95% CI 36.1 to 52.5); certainty not graded.

1 finding from 1 review

Intraglandular botulinum neurotoxin (BoNT) injection vs No BoNT (placebo or pre-treatment baseline)

Development of >=1 new carious lesion (caries incidence) · Patients with drooling (sialorrhea) due to neurological disease

In one RCT, BoNT-B 2500 U was not associated with a statistically significant increase in new caries versus placebo (RR 2.4, 95% CI 0.48 to 11.80; not significant).

2 findings from 1 review

LTF rs11716497 variant vs Reference allele/genotype

Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

LTF rs11716497 showed no significant association with dental caries in a single study (OR 1.04, 95% CI 0.90 to 1.21; ungraded).

1 finding from 1 review

Intervention not reported

Dental caries in permanent teeth · Children (permanent dentition) worldwide

In Australia, the pooled estimate of permanent-teeth caries prevalence in children was 54.9% (95% CI 50.9 to 58.8) from a single study; certainty not graded.

1 finding from 1 review

LTF rs1126477 variant vs Reference allele/genotype

Dental caries · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

LTF rs11216477 was significantly associated with dental caries in a single study (OR 1.17, 95% CI 1.06 to 1.29; ungraded).

1 finding from 1 review