Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,587 questions · 5,761 findings · 495 reviews

No studies found 1,011 · 17.5%GRADE not reported 1,797 · 31.2%Very low 1,100 · 19.1%Low 1,052 · 18.3%Moderate 649 · 11.3%High 152 · 2.6%

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PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Recurrence · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
1 finding from 1 review

Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection

Recurrence · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes

Elective neck dissection (at time of primary tumour resection) probably leads to lower recurrence compared with therapeutic (delayed) neck dissection (moderate certainty).

1 finding from 1 review

Superselective neck dissection vs Elective selective neck dissection

Disease-free survival · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
1 finding from 1 review

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

Total mortality · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)

PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in total mortality compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).

1 finding from 1 review

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Adverse events associated with treatment · Adults with oral cavity cancer
1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Short‐term mortality (30‐day or in‐hospital) · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in short‐term mortality (30‐day or in‐hospital) compared with cut‐down femoral artery access (low certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Failure of aneurysm exclusion ( · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in failure of aneurysm exclusion( compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Wound infection · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in wound infection (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Major complications · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in major complications (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Medium‐ to long‐term complications( · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in medium‐ to long‐term complications( compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Bleeding complications (30‐day or in‐hospital) · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in bleeding complications (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review