Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,227 questions · 2,562 findings · 156 reviews · All outcomes

No studies found 297 · 11.6%GRADE not reported 1,616 · 63.1%Very low 405 · 15.8%Low 144 · 5.6%Moderate 81 · 3.2%High 19 · 0.7%

Secondary education vs University education

Prevalence of untreated decay (% DT > 0) · Adults aged 25 years and older in Australia, Canada, New Zealand, and the United States

In United States, secondary versus university education differed by 10.4 percentage points in prevalence of untreated decay.

4 findings from 1 review
Show 1 more finding

Self-management (self-administered/self-monitored OHA) vs Professional OHA

Patient-reported behaviour changes · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review

Personalised one-to-one OHA vs Routine one-to-one OHA

Gingivitis · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether personalised one-to-one OHA changes periodontal health: gingivitis compared with routine one-to-one OHA (very low certainty).

1 finding from 1 review

Personalised one-to-one OHA vs Routine one-to-one OHA

Dental caries · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review

Enhanced one-to-one OHA vs Routine one-to-one OHA

Gingivitis · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether enhanced one-to-one OHA changes periodontal health: gingivitis compared with one-to-one OHA (standard) (very low certainty).

1 finding from 1 review

Enhanced one-to-one OHA vs Routine one-to-one OHA

Plaque · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether enhanced one-to-one OHA changes periodontal health: plaque levels compared with one-to-one OHA (standard) (very low certainty).

1 finding from 1 review

Enhanced one-to-one OHA vs Routine one-to-one OHA

Patient-reported changes in knowledge, attitudes and quality of life · Children or adults (fit and healthy, or with a well-defined medical condition)
1 finding from 1 review

Personalised one-to-one OHA vs Routine one-to-one OHA

Plaque · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether personalised one-to-one OHA changes periodontal health: plaque levels compared with routine one-to-one OHA (very low certainty).

1 finding from 1 review

Self-management (self-administered/self-monitored OHA) vs Professional OHA

Plaque · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether self-management (self-administered/self-monitored OHA) changes periodontal health: plaque levels compared with professional OHA (very low certainty).

1 finding from 1 review

Keratinocyte growth factor (KGF; palifermin or repifermin), intravenous vs placebo

Normalcy of diet (mean worst ability to eat, 1 to 4 scale) · Adults with cancer receiving treatment

Keratinocyte growth factor (KGF; palifermin or repifermin),… showed no clear difference in normalcy of diet (mean worst ability to eat, 1 to 4 scale) compared with placebo; GRADE not reported.

1 finding from 1 review

G‐CSF vs placebo or no treatment

Interruptions to cancer treatment (radiotherapy interruptions) · Adults with cancer receiving treatment

Granulocyte-colony stimulating factor (G-CSF) showed no clear difference in interruptions to cancer treatment (radiotherapy interruptions) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash vs Sucralfate mouthwash

Interruptions to cancer treatment · Adults receiving radiotherapy to the head and neck

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash showed no clear difference in interruptions to cancer treatment compared with sucralfate mouthwash; GRADE not reported.

1 finding from 1 review