Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Therapist support (visits) showed no clear difference in average pain scores (0-100 VAS) compared with control (treatment as usual); GRADE not reported.
1 finding from 1 review
Mycological: eradication of oral candidiasis · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis
Fluconazole (absorbed from GI tract) led to higher mycological: eradication of oral candidiasis compared with itraconazole (absorbed from GI tract); GRADE not reported.
1 finding from 1 review
Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Resorbable barrier (guided bone regeneration) led to lower major complications at the implant/donor site compared with resorbable barrier + autogenous bone; GRADE not reported.
1 finding from 1 review
Four complications occurred: two dehiscences in the resorbable group; one abscess and one dehiscence in the resorbable + autogenous bone group; none in the non-resorbable group. No statistically significant differences…
1 study · 24 participants
GRADE not reported
Aesthetics assessed by dentist: interproximal papilla dimension · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate-delayed implants (placed within 8 weeks after tooth… led to lower aesthetics assessed by dentist: interproximal papilla dimension compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.
1 finding from 1 review
Improvement in mucositis · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Tetrachlorodecaoxide showed no clear difference in improvement in mucositis compared with placebo; GRADE not reported.
1 finding from 1 review
Improvement in mucositis · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Sucralfate showed no clear difference in improvement in mucositis compared with placebo; GRADE not reported.
1 finding from 1 review
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Morning radiotherapy showed no clear difference in total mortality compared with afternoon radiotherapy; GRADE not reported.
1 finding from 1 review
Implant failure · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate-delayed implants (placed within 8 weeks after tooth… led to lower implant failure compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.
1 finding from 1 review
Three early implant failures (two immediate-delayed, one delayed); no statistically significant difference up to 5 years (Schropp 2003).
1 study · 46 participants
GRADE not reported
Average pain scores (0-100 VAS) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Chlorhexidine mouthwash showed no clear difference in average pain scores (0-100 VAS) compared with salt and soda mouthwash; GRADE not reported.
1 finding from 1 review
Mucositis severity (mild to moderate) · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Low level laser therapy led to higher mucositis severity (mild to moderate) compared with sham (placebo) laser treatment; GRADE not reported.
1 finding from 1 review
Major complication at augmented site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) led to lower major complications at the augmented site compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
Two complications occurred in the Bio-Oss plus barrier group (one abscess during healing; one chronic perimplant mucositis); none in the Bio-Oss group. No statistically significant difference.
1 study · 20 participants
GRADE not reported
Disease-free survival · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
1 finding from 1 review
Hyperfractionated/accelerated/split vs conventional, disease free survival: two trials (Fu 2000, Olmi 2003); results contradictory with substantial statistical heterogeneity (P = 0.02, I2 = 82%); no pooled estimate…
2 studies
GRADE not reported
Jaw pain (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral clonazepam (benzodiazepine) showed no clear difference in jaw pain (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Open reduction and fixation vs Closed (conservative) management (no active intervention other than soft diet, analgesics or antibiotics; or intermaxillary/maxillary-mandibular fixation with rigid or elastic traction)
Outcome not reported · Adults, over 18 years of age, with unilateral or bilateral fractures of the mandibular condyles
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Aesthetics assessed by dentist: position of the perimplant tissues · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate-delayed implants (placed within 8 weeks after tooth… led to higher aesthetics assessed by dentist: position of the perimplant tissues compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.
1 finding from 1 review
Reduction in pain duration (percentage of day) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral propranolol (beta-blocker) showed no clear difference in reduction in pain duration (percentage of day) compared with placebo; GRADE not reported.
1 finding from 1 review
Improvement in mucositis · People with cancer receiving chemotherapy or radiotherapy (or both) who have oral mucositis
Granulocyte macrophage-colony stimulating factor (GM-CSF) led to higher improvement in mucositis compared with placebo or no treatment; GRADE not reported.
2 findings from 1 review
Marginal bone level change · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate-delayed implants (placed within 8 weeks after tooth… showed no clear difference in perimplant marginal bone level changes compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.
1 finding from 1 review
Adverse events ‐ treatment emergent · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review
Tchivileva et al 2010: at least one treatment-emergent adverse event was reported by five participants (12.5%) during the propranolol period (nausea, diarrhoea, insomnia, dizziness, fatigue) and four participants (10%)…
1 study · 40 participants
GRADE not reported
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Split-course radiotherapy showed no clear difference in total mortality compared with accelerated radiotherapy; GRADE not reported.
1 finding from 1 review