Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,710 questions · 14,842 findings · 1,394 reviews

No studies found 2,880 · 19.4%GRADE not reported 1,413 · 9.5%Very low 3,103 · 20.9%Low 3,870 · 26.1%Moderate 2,663 · 17.9%High 913 · 6.2%

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NSAIDs vs placebo

Visual improvement at end of treatment, as defined by two or more Snellen lines · participants with chronic CME (≥ 4 months) following cataract surgery

It is very uncertain whether NSAID changes visual improvement at end of treatment, as defined by two or more… compared with placebo (very low certainty).

1 finding from 1 review

NSAIDs vs placebo

Persistence of visual improvement one month after discontinuation of treatment · participants with chronic CME (≥ 4 months) following cataract surgery

It is very uncertain whether NSAID changes persistence of visual improvement one month after discontinuation of… compared with placebo (very low certainty).

1 finding from 1 review

Music therapy vs placebo or usual care

Global improvement · Individuals with autism spectrum disorder

Music therapy probably leads to higher global improvement compared with placebo therapy or standard care (moderate certainty).

1 finding from 1 review

Music therapy vs placebo or usual care

Autism symptom severity Measured by: parent‐reported autism symptoms on standardised autism screening and diagnostic instruments (lower scores indicate less severe autism symptoms) · Individuals with autism spectrum disorder
1 finding from 1 review

Music therapy vs placebo or usual care

Adverse events Any serious or non‐serious adverse event · Individuals with autism spectrum disorder

Music therapy showed no clear difference in adverse events Any serious or non‐serious adverse event compared with placebo therapy or standard care (moderate certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement in disability scale used in the original study · people with multifocal motor neuropathy

IVIg showed no clear difference in proportion of participants with an improvement in disability scale… compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement of muscle strength · people with multifocal motor neuropathy

IVIg may leads to higher proportion of participants with an improvement of muscle strength compared with placebo (low certainty).

1 finding from 1 review

IVIg vs placebo

Proportion of participants with an improvement in disability at 12 months or later · people with multifocal motor neuropathy

The review found no eligible studies for this question.

1 finding from 1 review

IVIg vs placebo

Proportion of participants in which at least 1 conduction block resolved after therapy · people with multifocal motor neuropathy

IVIg showed no clear difference in proportion of participants in which at least 1 conduction block… compared with placebo (low certainty).

1 finding from 1 review