Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,752 questions · 6,648 findings · 688 reviews

No studies found 1,125 · 16.9%GRADE not reported 670 · 10.1%Very low 1,796 · 27%Low 1,685 · 25.3%Moderate 1,075 · 16.2%High 297 · 4.5%

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Intervention not reported

Treatment discontinuation due to adverse event (safety population) · women with metastatic triple‐negative breast cancer (mTNBC)

The intervention probably leads to lower treatment discontinuation due to adverse event (safety population) (moderate certainty).

1 finding from 1 review

Intervention not reported

Treatment‐related death (safety population) · women with metastatic triple‐negative breast cancer (mTNBC)

The intervention may leads to higher treatment‐related death (safety population) (low certainty).

1 finding from 1 review

Intervention not reported

Nausea/vomiting* grade 3 or 4 (safety population) · women with metastatic triple‐negative breast cancer (mTNBC)

The intervention may leads to higher nausea/vomiting* grade 3 or 4 (safety population) (low certainty).

1 finding from 1 review

Intervention not reported

Anaemia grade 3 or 4 (safety population) · women with metastatic triple‐negative breast cancer (mTNBC)

The intervention may leads to higher anaemia grade 3 or 4 (safety population) (low certainty).

1 finding from 1 review

Intervention not reported

Leukopaenia (safety population) · women with metastatic triple‐negative breast cancer (mTNBC)

The intervention probably leads to higher leukopaenia (safety population) (moderate certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality · people with liver metastases

The intervention showed no clear difference in all‐cause mortality (low certainty).

1 finding from 1 review

Intervention not reported

Cancer mortality · people with liver metastases

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

All adverse events and complications · people with liver metastases

The intervention led to higher all adverse events and complications; GRADE not reported.

1 finding from 1 review

Intervention not reported

Health‐related quality of life · people with liver metastases

The review found no eligible studies for this question.

1 finding from 1 review