Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Therapeutic ultrasound vs placebo

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic low‐back pain

It is very uncertain whether therapeutic ultrasound changes pain intensity Scale: VAS (100‐point scale; higher scores mean… compared with placebo (very low certainty).

1 finding from 1 review

Therapeutic ultrasound plus exercise vs exercise

Well‐being Scale: general health subscale of SF‐36 (higher scores mean worse well‐being) · adults with chronic low‐back pain

It is very uncertain whether therapeutic ultrasound plus exercise changes well‐being Scale: general health subscale of SF‐36 (higher scores… compared with exercise alone (very low certainty).

1 finding from 1 review

Therapeutic ultrasound vs placebo

At least 30% reduction in pain · adults with chronic low‐back pain

Therapeutic ultrasound showed no clear difference in pain intensity Scale: VAS (number of responders at 30% reduction of… compared with placebo (moderate certainty).

1 finding from 1 review

Therapeutic ultrasound vs placebo

Back‐specific functional status · adults with chronic low‐back pain

Therapeutic ultrasound showed no clear difference in back‐specific functional status Scale: Functional Rating Index,… compared with placebo (low certainty).

1 finding from 1 review

Therapeutic ultrasound vs placebo

Well‐being Scale: general health subscale of SF‐36 (higher scores mean worse well‐being) · adults with chronic low‐back pain

Therapeutic ultrasound showed no clear difference in well‐being Scale: general health subscale of SF‐36 (higher scores… compared with placebo (moderate certainty).

1 finding from 1 review

Therapeutic ultrasound plus exercise vs exercise

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic low‐back pain

It is very uncertain whether therapeutic ultrasound plus exercise changes pain intensity Scale: VAS (100‐point scale; higher scores mean… compared with exercise alone (very low certainty).

1 finding from 1 review

Levosimendan vs dobutamine

All‐cause short‐term mortality: range 15 to 31 days · people with cardiogenic shock or low cardiac output syndrome

Levosimendan showed no clear difference in all‐cause short‐term mortality: range 15 to 31 days compared with dobutamine (low certainty).

1 finding from 1 review