Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,320 questions · 4,561 findings · 388 reviews

No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%

Posterior reconstruction vs no posterior reconstruction

Urinary continence 3 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Posterior reconstruction showed no clear difference in urinary continence 3 months after surgery MCID: 5% absolute difference compared with no posterior reconstruction (low certainty).

1 finding from 1 review

Posterior reconstruction vs no posterior reconstruction

Serious adverse events · men (ages > 18 years) with clinically localized prostate cancer

Posterior reconstruction showed no clear difference in serious adverse events compared with no posterior reconstruction (moderate certainty).

1 finding from 1 review

Posterior reconstruction vs no posterior reconstruction

Urinary continence 6 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Posterior reconstruction showed no clear difference in urinary continence 6 months after surgery MCID: 5% absolute difference compared with no posterior reconstruction (moderate certainty).

1 finding from 1 review

Posterior reconstruction vs no posterior reconstruction

Urinary continence 12 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Posterior reconstruction showed no clear difference in urinary continence 12 months after surgery MCID: 5% absolute… compared with no posterior reconstruction (low certainty).

1 finding from 1 review

Posterior reconstruction vs no posterior reconstruction

Potency 12 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

It is very uncertain whether posterior reconstruction changes potency recovery 12 months after surgery MCID: 5% absolute difference compared with no posterior reconstruction (very low certainty).

1 finding from 1 review

Posterior reconstruction vs no posterior reconstruction

Positive surgical margins MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Posterior reconstruction showed no clear difference in positive surgical margins MCID: 5% absolute difference compared with no posterior reconstruction (low certainty).

1 finding from 1 review

Self-ligating brackets vs Conventional brackets

Amount of crowding (lower incisor crowding) at 10 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether self-ligating brackets changes amount of crowding (lower incisor crowding) at 10 weeks compared with conventional brackets (very low certainty).

1 finding from 1 review

ARP with alloplast vs ARP with xenograft

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with alloplast vs Extraction alone

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with alloplast changes changes in vertical height of alveolar ridge (mm) compared with extraction alone (very low certainty).

1 finding from 1 review

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with alloplast plus barrier membrane vs ARP with alloplast without membrane

Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with alloplast plus barrier membrane changes changes in bucco-lingual/palatal width of alveolar ridge (mm) compared with ARP with alloplast without membrane (very low certainty).

1 finding from 1 review

Haas expander anchored on deciduous second molars vs Haas expander anchored on permanent first molars

Canine expansion · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
  • Orthodontic treatment for posterior crossbites 2021 · Cochrane All outcomes
    after 5-month retention period
    Ugolini 2015: deciduous 4.2 mm vs permanent 3.3 mm; P<0.01 (more stable anterior expansion with deciduous anchorage)
    1 study
    GRADE not reported

Self-ligating brackets (Damon System) vs Fixed tooth-borne expansion (Hyrax)

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review
  • Nam 2020: Damon 41/41 vs Hyrax 41/41; NS (no difference in crossbite correction; greater transverse molar/premolar expansion with Hyrax)
    1 study · 82 participants
    GRADE not reported

Bonded Minne appliance (slow maxillary expansion) vs Banded Minne appliance (slow maxillary expansion)

Stability of crossbite correction (relapse of molar expansion) · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…
1 finding from 1 review

Fixed tooth-bone-borne expansion vs Fixed tooth-borne expansion (Hyrax)

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Fixed tooth-bone-borne expansion showed no clear difference in crossbite correction compared with fixed tooth-borne expansion (Hyrax) (low certainty).

1 finding from 1 review

Direct composite resin restoration vs Amalgam restoration

Fracture of restorations · People with permanent or adult posterior teeth requiring restoration (parallel-group trials involved children aged 6 to 12 years)

Direct composite resin restoration showed no clear difference in fracture of restorations compared with amalgam restoration (low certainty).

1 finding from 1 review

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with alloplast vs Extraction alone

Complications (e.g. discomfort, pain and swelling) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…
1 finding from 1 review

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with allograft plus synthetic cell-binding peptide P-15 changes changes in vertical height of alveolar ridge (mm) compared with ARP with allograft without P-15 (very low certainty).

1 finding from 1 review