Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,209 questions · 2,322 findings · 227 reviews · Headline outcomes only

No studies found 644 · 27.7%GRADE not reported 135 · 5.8%Very low 591 · 25.5%Low 582 · 25.1%Moderate 309 · 13.3%High 61 · 2.6%

Intervention not reported

≥ 1 of cough, fever, or decreased playfulness · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review

Intervention not reported

≥ 1 of cough, fever, poor weight gain, or tuberculosis close contact (WHO 4‐symptom symptom screen) · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review

Intervention not reported

Estimation (95% Cl) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pooled sensitivity 87% (75% to 93%) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…
1 finding from 1 review

Intervention not reported

Pooled specificity 99% (68% to 100%) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…
1 finding from 1 review

Intervention not reported

Estimations · children evaluated in inpatient or outpatient settings Index tests: Xpert MTB/RIF Role: an initial test Threshold for index tests: an…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Sensitivities 43% and 100% · children evaluated in inpatient or outpatient settings Index tests: Xpert MTB/RIF Role: an initial test Threshold for index tests: an…
1 finding from 1 review