Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,447 questions · 2,590 findings · 266 reviews

No studies found 699 · 27%GRADE not reported 289 · 11.2%Very low 614 · 23.7%Low 605 · 23.4%Moderate 322 · 12.4%High 61 · 2.4%

Budesonide 9 mg vs steroids

Withdrawal due to disease worsening · Patients with active Crohn's disease

It is very uncertain whether budesonide 9 mg changes withdrawal due to disease worsening compared with conventional steroids (very low certainty).

1 finding from 1 review

Budesonide 9 mg vs mesalamine

Clinical remission · Patients with active Crohn's disease

Budesonide 9 mg probably leads to higher induction of clinical remission (CDAI < 150) ‐ 8 weeksThomsen 1998 compared with mesalamine (moderate certainty).

2 findings from 1 review

Budesonide 9 mg vs mesalamine

Clinical improvement (decrease in CDAI > 100 or total CDAI < 150) · Patients with active Crohn's disease

Budesonide 9 mg showed no clear difference in clinical improvement (decrease in CDAI > 100 or total CDAI < 150) compared with mesalamine (moderate certainty).

1 finding from 1 review

Budesonide 9 mg vs placebo

Clinical improvement (decrease in CDAI > 100 or total CDAI < 150) · Patients with active Crohn's disease

Budesonide 9 mg probably leads to higher clinical improvement (decrease in CDAI > 100 or total CDAI < 150) ‐… compared with placebo (moderate certainty).

1 finding from 1 review

Massage vs inactive control

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with LBP
1 finding from 1 review