Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,782 questions · 1,852 findings · 128 reviews · Effective Practice and Organisation of Care

No studies found 557 · 30.1%GRADE not reported 53 · 2.9%Very low 446 · 24.1%Low 476 · 25.7%Moderate 255 · 13.8%High 65 · 3.5%

Intervention not reported

Anthropometric recovery: percentage of children who recover from moderate or severe wasting Defined as % children aged 6–59 months who recovered in treatment programmes for moderate or severe malnutrition (Wroe 2021) · children aged > 6 months and ≤ 5 years with wasting
1 finding from 1 review

Intervention not reported

Relapse Defined as MUAC < 115 mm within 2 months after recovery (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in relapse Defined as MUAC < 115 mm within 2 months after recovery… (moderate certainty).

1 finding from 1 review

Intervention not reported

Transfer to inpatient care Defined as referral for complications such as fever, pneumonia, anorexia or dehydration (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in transfer to inpatient care Defined as referral for complications… (moderate certainty).

1 finding from 1 review

Intervention not reported

Default from care Defined as absence on 2 consecutive visits (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention showed no clear difference in default from care Defined as absence on 2 consecutive visits… (moderate certainty).

1 finding from 1 review

Intervention not reported

Anthropometric recovery: improvement from severe wasting Defined as MUAC ≥ 115 mm, clinically well, absence of oedema for 2 consecutive visits, and minimum stay of 8 weeks in the programme (Hussain 2021) · children aged > 6 months and ≤ 5 years with wasting

The intervention may leads to lower anthropometric recovery: improvement from severe wasting Defined as… (low certainty).

1 finding from 1 review

Intervention not reported

Anthropometric recovery Defined as: WHZ ≥ −1.5 or MUAC > 125 mm for 2 consecutive visits and absence of nutritional oedema for 14 days (Alvarez Moran 2018b); absence of oedema and WHZ ≥ −1.5 or MUAC > 125 mm (Charle‐Cuellar 2021c; no oedema and we... · children aged > 6 months and < 5 years with wasting

It is very uncertain whether the intervention changes anthropometric recovery Defined as: WHZ ≥ −1.5 or MUAC > 125 mm for… (very low certainty).

1 finding from 1 review

Intervention not reported

Non‐response to treatment Defined as: not achieving weight‐for‐height > 85% of ideal or relapse requiring inpatient treatment (Linneman 2007)a; persistent oedema at 21 days or no weight gain in 2 consecutive visits (Ogobara Dougnon 2021)d; not mee... · children aged > 6 months and < 5 years with wasting

It is very uncertain whether the intervention changes non‐response to treatment Defined as: not achieving… (very low certainty).

1 finding from 1 review

Intervention not reported

Anthropometric outcomes: MUAC gain per day Defined as (discharge MUAC − admission MUAC)/days in treatment among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting
1 finding from 1 review

Intervention not reported

Anthropometric outcomes: total weight gain (g/kg) Defined as (weight at discharge − weight on admission)/weight on admission among children with no oedema and discharged as cured (Charle‐Cuellar 2021)c · children aged > 6 months and < 5 years with wasting
1 finding from 1 review