Adverse effects sufficient to stop treatment · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate probably leads to higher adverse effects severe enough to stop treatment** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Postpartum haemorrhage · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in postpartum haemorrhage** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Any breastfeeding at hospital discharge · women at risk of preterm birth (< 34 weeks' gestation)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Women’s views of treatment** · women at risk of preterm birth (< 34 weeks' gestation)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Cerebral palsy · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate leads to lower cerebral palsy (up to 2 years' corrected age)** compared with placebo (outcomes (high certainty).
2 findings from 1 review
Major disability by 18 to 24 months corrected age (aligned definition) · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in major neurodevelopmental disability (up to 2 years' corrected age)** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Intraventricular haemorrhage, Papile grade 3/4 · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate probably leads to lower severe intraventricular haemorrhage (grade 3 or 4) (newborn/infant)** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Bronchopulmonary dysplasia/chronic lung disease · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in chronic lung disease/bronchopulmonary dysplasia (newborn/infant)** compared with placebo (outcomes (low certainty).
1 finding from 1 review
Death (fetal, neonatal, or later (up to school age))** · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in death (fetal, neonatal, or later (up to school age))** compared with placebo (outcomes (low certainty).
1 finding from 1 review
Cerebral palsy · preterm or very low birth weight infants
It is very uncertain whether summary of findings table ‐ Silicone earplugs changes cerebral palsy at 18 to 22 months' corrected age compared with no earplugs (very low certainty).
1 finding from 1 review
Mental Developmental Index (Bayley II) at 18 to 22 months' corrected age · preterm or very low birth weight infants
1 finding from 1 review
Normal auditory functioning at discharge · preterm or very low birth weight infants
It is very uncertain whether summary of findings table ‐ Silicone earplugs changes normal auditory functioning at discharge compared with no earplugs (very low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · preterm or very low birth weight infants
It is very uncertain whether summary of findings table ‐ Silicone earplugs changes all‐cause mortality during hospital stay compared with no earplugs (very low certainty).
1 finding from 1 review
Weight (kg) · preterm or very low birth weight infants
1 finding from 1 review
Height (cm) · preterm or very low birth weight infants
1 finding from 1 review
Duration of mechanical ventilation · preterm or very low birth weight infants
1 finding from 1 review
Days of initial hospitalisation · preterm or very low birth weight infants
1 finding from 1 review
Necrotising enterocolitis · very preterm or very low birth weight infants
1 finding from 1 review
Mortality before hospital discharge · very preterm or very low birth weight infants
1 finding from 1 review
Late‐onset invasive infection (before hospital discharge) · very preterm or very low birth weight infants
1 finding from 1 review