Findings

What do systematic reviews say?

185 questions · 186 findings · 5 reviews · Common Mental Disorders

No studies found 10 · 5.4%GRADE not reported 16 · 8.6%Very low 23 · 12.4%Low 38 · 20.4%Moderate 98 · 52.7%High 1 · 0.5%

Failure to respond at 16‐24 weeks · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Failure to remit at endpoint · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

SMD at endpoint · patients with depression

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 2109 participants
Moderate

Failure to complete ‐ any cause ‐ · patients with depression

Paroxetine showed no clear difference in failure to complete ‐ any cause ‐ total drop out rate compared with fluoxetine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 1.05 [0.89, 1.23]
13 studies · 2798 participants
Moderate

Participants with at least some Side Effects · patients with depression

Paroxetine showed no clear difference in participants with at least some Side Effects compared with fluoxetine (moderate certainty).

1 finding from 1 review

Paroxetine versus other anti‐depressive agents for depression 2014 · Cochrane Headline outcomes only
OR 0.94 [0.69, 1.28]
9 studies · 2255 participants
Moderate