Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Kidney and Transplant

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

Withdrew due to intolerance ( · preventing the progression of CKD

Metformin showed no clear difference in withdrew due to intolerance ( compared with active control (moderate certainty).

1 finding from 1 review

Metformin for preventing the progression of chronic kidney disease 2024 · Cochrane Headline outcomes only
RR 0.92 [0.79, 1.08]
3 studies · 5593 participants
Moderate

Withdrew due to intolerance ( · preventing the progression of CKD

Metformin probably leads to higher withdrew due to intolerance ( compared with placebo (moderate certainty).

1 finding from 1 review

Metformin for preventing the progression of chronic kidney disease 2024 · Cochrane Headline outcomes only
RR 2.19 [1.46, 3.27]
4 studies · 646 participants
Moderate