Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Pain, Palliative and Supportive Care

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 100%Moderate 0 · 0%High 0 · 0%

Withdrawals due to adverse events · adults with painful diabetic neuropathy

Topical clonidine (TC) showed no clear difference in withdrawals due to adverse events during longest compared with placebo (low certainty).

1 finding from 1 review

Topical clonidine for neuropathic pain in adults 2022 · Cochrane Headline outcomes only
RR 0.34 [0.04, 3.18]
1 study · 179 participants
Low