Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Gut

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Azathioprine or 6‐mercaptopurine vs methotrexate

Withdrawals due to adverse events · Patients with active Crohn's disease

It is very uncertain whether azathioprine or 6‐mercaptopurine changes withdrawals due to adverse events compared with methotrexate (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for induction of remission in Crohn's disease 2016 · Cochrane Headline outcomes only
RR 0.78 [0.23, 2.71]
2 studies · 85 participants
Very low

6‐Mercaptopurine vs methotrexate

Withdrawals due to adverse events · maintenance of remission in Crohn's disease

It is very uncertain whether 6‐Mercaptopurine changes withdrawals due to adverse events compared with methotrexate (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 0.68 [0.17, 2.75]
1 study · 57 participants
Very low