Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 0 · 0%High 1 · 50%

Intermittent/cyclic etidronate 400 mg/day vs placebo

Withdrawals due to adverse events · postmenopausal women with a higher risk for fracturesa

It is very uncertain whether intermittent/cyclic etidronate 400 mg/day changes withdrawals due to adverse events compared with placebo (very low certainty).

1 finding from 1 review

Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women 2024 · Cochrane Headline outcomes only
RR 1.09 [0.54, 2.18]
Studies not reported
Very low

Risedronate 5 mg/day vs placebo

Withdrawals due to adverse events · pPostmenopausal women at higher risk of fractures1

Risedronate 5 mg/day showed no clear difference in withdrawals due to adverse events compared with placebo (high certainty).

1 finding from 1 review

Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women 2022 · Cochrane Headline outcomes only
RR 0.98 [0.9, 1.07]
Studies not reported
High