Findings

What do systematic reviews say?

24 questions · 24 findings · 4 reviews

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No studies found 1 · 4.2%GRADE not reported 1 · 4.2%Very low 16 · 66.7%Low 6 · 25%Moderate 0 · 0%High 0 · 0%

Corticosteroids vs placebo

Withdrawals due to adverse events · inactive EoE patients

Corticosteroids may leads to lower withdrawals due to adverse events 12 to 50 weeks compared with placebo (low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.37 [0.16, 0.87]
3 studies · 280 participants
Low

Biologics vs placebo

Withdrawals due to adverse events · active EoE patients

Biologics showed no clear difference in withdrawals due to adverse events 12 to 44 weeks compared with placebo (low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 1.55 [0.88, 2.74]
8 studies · 792 participants
Low

Corticosteroids vs placebo

Withdrawals due to adverse events · active EoE patients

Corticosteroids may leads to lower withdrawals due to adverse events (2 to 12 weeks) compared with placebo (low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 0.64 [0.43, 0.96]
14 studies · 1032 participants
Low

Four‐food elimination diet with omeprazole vs omeprazole

Withdrawals due to adverse events · active EoE patients

It is very uncertain whether four‐food elimination diet with omeprazole changes withdrawals due to adverse events at 8 to 12 weeks compared with omeprazole (very low certainty).

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
RR 5 [0.62, 40.44]
1 study · 64 participants
Very low